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diacylglycerol phosphorylation

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-107613
    R 59-022
    2 Publications Verification

    DKGI-I; diacylglycerol kinase inhibitor I

    		 PKC 5-HT Receptor Inflammation/Immunology
    R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils .
    R 59-022
  • HY-100960
    Dioctanoylglycol

    Ethylene glycol dicaprylate; Ethylene glycol dioctanoate; Ethylenedioctanoate

    		 DGK Cardiovascular Disease
    Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM) .
    Dioctanoylglycol
  • HY-107613A
    R 59-022 hydrochloride
    2 Publications Verification

    DKGI-I hydrochloride; diacylglycerol kinase inhibitor I hydrochloride

    		 PKC 5-HT Receptor Infection Inflammation/Immunology Cancer
    R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 µM). R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils .
    R 59-022 hydrochloride
  • HY-W339757
    Dioctanoylphosphatidic acid sodium

    		mTOR Endogenous Metabolite Cancer
    Dioctanoylphosphatidic acid sodium functions as a modulator of phagocyte respiratory burst, acts as a precursor to diacylglycerol and lysophosphatidic acid, and influences the phosphorylation of the mammalian target of rapamycin (mTOR) while enhancing the viability of gallbladder carcinoma cells treated with histone deacetylase inhibitors (HDACIs); it is derived from glycerophospholipid through the action of phospholipase D.
    Dioctanoylphosphatidic acid sodium
  • HY-107613R
    R 59-022 (Standard)

    DKGI-I (Standard); diacylglycerol kinase inhibitor I (Standard)

    		 PKC 5-HT Receptor Reference Standards Inflammation/Immunology
    R 59-022 (Standard) is the analytical standard of R 59-022. This product is intended for research and analytical applications. R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils .
    R 59-022 (Standard)
  • HY-100960R
    Dioctanoylglycol (Standard)

    Ethylene glycol dicaprylate (Standard); Ethylene glycol dioctanoate (Standard); Ethylenedioctanoate (Standard); (Standard)

    		 DGK Reference Standards Cardiovascular Disease
    Dioctanoylglycol (Standard) is the analytical standard of Dioctanoylglycol (HY-100960). This product is intended for research and analytical applications. Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM) .
    Dioctanoylglycol (Standard)
  • HY-E70949
    Protein Kinase C,Rat

    		PKC Metabolic Disease
    Protein Kinase C,Rat (EC 2.7.1.37) is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. Protein Kinase C in turn are activated by signals such as increases in the concentration of diacylglycerol (DAG) or calcium ions (Ca 2+).
    Protein Kinase C,Rat
  • HY-107613AR
    R 59-022 hydrochloride (Standard)

    DKGI-I hydrochloride (Standard); diacylglycerol kinase inhibitor I hydrochloride (Standard)

    		 Reference Standards PKC 5-HT Receptor Infection Inflammation/Immunology Cancer
    R 59-022 hydrochloride (Standard) is the analytical standard of R 59-022 (hydrochloride) (HY-107613A). This product is intended for research and analytical applications. R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 µM). R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein Kinase C (PKC). R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils .
    R 59-022 hydrochloride (Standard)

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