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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
dystrophin protein
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "dystrophin protein" in MCE Product Catalog:
Cat. No.: HY-132586
CAS No.: 2055732-84-6
Synonyms: NS-065/NCNP-01
Research Areas:
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .
Cat. No.: HY-132586A
Purity: 95.25%
Synonyms: NS-065/NCNP-01 sodium
Research Areas:
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .
Cat. No.: HY-147253
CAS No.: 2409088-11-3
Synonyms: NS 089; NCNP 02
Target:
Research Areas:
Brogidirsen (NS 089; NCNP 02) is a a dual-targeting antisense oligonucleotide. Brogidirsen can induce dystrophin protein experession. Brogidirsen can be used for the research of Duchenne muscular dystrophy .
Cat. No.: HY-132584A
Purity: 99.07%
Synonyms: SRP-4045 sodium
Target:
Research Areas:
Casimersen (SRP-4045) sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .
Cat. No.: HY-177649
CAS No.: 3053113-45-1
Target:
Research Areas:
Nivudirsen is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
Cat. No.: HY-123359
CAS No.: 414909-09-4
Target:
Research Areas:
RTC14 is a read-through compound (RTC) that can induce ribosomes to bypass nonsense mutations in mRNA and allow the production of full-length functional proteins. RTC14 has the potential to be used in the research of various genetic disorders, such as nonsense mutations in the ataxia-telangiectasia mutated (ATM) gene and the dystrophin gene .
Cat. No.: HY-177649A
Target:
Research Areas:
Nivudirsen sodium is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
Cat. No.: HY-147253A
Synonyms: NS 089 sodium; NCNP 02 sodium
Target:
Research Areas:
Brogidirsen (NS 089; NCNP 02) sodium is a a dual-targeting antisense oligonucleotide. Brogidirsen sodium can induce dystrophin protein experession. Brogidirsen sodium can be used for the research of Duchenne muscular dystrophy .
Cat. No.: HY-132584
CAS No.: 1422958-19-7
Synonyms: SRP-4045
Target:
Research Areas:
Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .
Cat. No.: HY-P75311
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DAG1; Alpha-Dystroglycan; Dystroglycan 1; Beta-Dystroglycan; 156DAG; Dystroglycan; AGRNR; dystrophin; A3a; LGMDR16; DAG; MDDGA9; Dystroglycan 1 (dystrophin-Associated Glycoprotein 1); MDDGC7; dystrophin-Associated Glycoprotein-1; MDDGC9; dystrophin-Associ
Species:
Human
Source:
HEK293
Cat. No.: HY-185933
CAS No.: 2848572-30-3
Target:
Research Areas:
Tuledirsen delvopertide is an exon-skipping oligonucleotide-transmembrane peptide conjugate. Tuledirsen delvopertide stimulates the synthesis of dystrophin, a protein that plays a role in muscle cell membrane stability. Tuledirsen delvopertide can be used for the study of Duchenne muscular dystrophy .
Cat. No.: HY-177972
Research Areas:
Zotadirsen is the core component of the AOC drug Delpacibart zotadirsen (AOC1044) (HY-177564), consisting of a phosphorodiamidate morpholino oligonucleotide (PMO) targeting exon 44 of the dystrophin gene and an SMCC linker (HY-42360). Upon conjugation with the anti-TfR1 antibody Delpacibart (HY-P990051), Zotadirsen exerts splicing regulatory activity and mediates exon skipping. Zotadirsen can be used in studies related to AOC synthesis .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
