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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
granulosa cells
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "granulosa cells" in MCE Product Catalog:
149
149 Publications Verification
Synonyms: N-Acetyl-5-methoxytryptamine
122
122
5
5 Cited Publications
BSJ-03-123 is a selective PROTAC degrader of CDK6. BSJ-03-123 degrades CDK6, thereby inhibiting Rb S780 phosphorylation and inducing G1 phase arrest, while remodeling cell cycle and transcriptional signaling, with no effect on CDK4-dependent cancer cells. BSJ-03-123 reduces CDK6 protein levels in mouse ovarian tissues, increases the proportion of primordial follicles, and induces granulosa cell apoptosis, without impairing the ability of oocytes to resume meiosis and mature to the MII stage. BSJ-03-123 alleviates uveitis by blocking the HDACs-CDK6/ID2 axis. BSJ-03-123 can be used in studies related to acute myeloid leukemia, mantle cell lymphoma and autoimmune uveitis .
3
3 Cited Publications
Cat. No.: HY-N0830S6
CAS No.: 56599-85-0
3
3 Cited Publications
Cat. No.: HY-N0830BS1
CAS No.: 2483736-17-8
3
3 Cited Publications
Cat. No.: HY-W134007S1
CAS No.: 1458714-74-3
2
Target:
Research Areas:
2
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-N0830S2
CAS No.: 39756-30-4
1
1 Cited Publications
Cat. No.: HY-W127758
CAS No.: 9005-32-7
1
1 Cited Publications
Cat. No.: HY-N0830S18
CAS No.: 358730-99-1
1
1 Cited Publications
Cat. No.: HY-N0830S3
CAS No.: 57677-53-9
1
1 Cited Publications
Cat. No.: HY-N0830S12
CAS No.: 75736-47-9
Synonyms: Vinylcyclohexene diepoxide
Research Areas:
Neurological Disease Inflammation/Immunology Endocrinology Cancer
4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders .
Cat. No.: HY-N0830S9
CAS No.: 287100-87-2
Cat. No.: HY-N0830S5
CAS No.: 75736-53-7
Cat. No.: HY-B0075S1
CAS No.: 90735-69-6
Synonyms: N-Acetyl-5-methoxytryptamine-d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
