7 Results for "

guanosine-3'

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "guanosine-3'" in MCE Product Catalog:

Cat. No.: HY-W013330
CAS No.: 3608-58-0
Synonyms: guanosine, 3'-deoxy-
3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a derivative of Guanosine (HY-N0097). 3′-Deoxyguanosine interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. 3′-Deoxyguanosine exhibits moderate displacement activity for [ 3H]-guanosine in rat meninges. 3′-Deoxyguanosine is useful for studying the mechanism of guanosine receptors and purine metabolism [3].
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Cat. No.: HY-133190
CAS No.: 1351373-46-0
Purity:  ≥98.0%
Target:  

PROTAC Linkers

Research Areas:  

Metabolic Disease

Bis-propargyl-PEG7 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG7 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-117186
CAS No.: 400775-35-1
Target:  

PROTAC Linkers

Research Areas:  

Metabolic Disease

Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-W800446
CAS No.: 709641-79-2
Synonyms: Lna-g amidite
Research Areas:  

Others

LNA-Guanosine 3'-CE phosphoramidite (Lna-g amidite) is an essential building block to Locked Nucleic Acid (LNA) oligonucleotide synthesis, which includes a ribonucleoside linked by a methylene unit between the 2’-oxygen and 4’-carbon atoms, paralleling DNA polymer assembly.
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Cat. No.: HY-154628
CAS No.: 2382942-32-5
Research Areas:  

Cancer

N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-W654000
Synonyms: guanosine 3',5'-cyclic-13C,15N2 monophosphate
Cyclic GMP- 13C, 15N2 is 13C and 15N labeled Cyclic GMP (HY-113469). Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses [3] .
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Cat. No.: HY-114265
CAS No.: 32452-17-8
Synonyms: ppGpp
Guanosine 3',5'-bisdiphosphate (ppGpp) is a guanosine derivative that inhibits guanylate kinase. Guanosine 3',5'-bisdiphosphate binds to the β' subunit of plastid-encoded bacterial-type RNA polymerase, inhibits the catalytic activity of guanylate kinase, and regulates chloroplast translation and GTP biosynthesis. Guanosine 3',5'-bisdiphosphate acts as a plant chloroplast signaling molecule and a global bacterial regulator, and plays a role in microbial persistence. Guanosine 3',5'-bisdiphosphate is applicable to biosynthesis-related research [3].
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