17 Results for "

hepatocyte growth factor activator

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "hepatocyte growth factor activator" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-114363A
CAS No.: 1832686-44-8
Purity:  98.53%
Target:  

c-Met/HGFR

Research Areas:  

Cancer

SRI 31215 (TFA) is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC50 values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer .
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2
2 Cited Publications
Cat. No.: HY-P70832
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HABP2; factor VII Activating Protein; Hyaluronan Binding Protein 2; Hyaluronan-Binding Protein 2; HGFAL; FVII activator; PHBP; PHBSP; FSAP; Hyaluronic Acid Binding Protein 2; HABP; Plasma Hyaluronan-Binding Protein; hepatocyte growth factor activator-Like
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-137455
CAS No.: 1070881-42-3
Purity:  99.89%
Synonyms: ANG-3777
Target:  

c-Met/HGFR

Research Areas:  

Inflammation/Immunology

Terevalefim (ANG-3777), an hepatocyte growth factor (HGF) mimetic, selectively activates the c-Met receptor .
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Cat. No.: HY-P99196
CAS No.: 1174900-84-5

Target:  

c-Met/HGFR

Research Areas:  

Cancer

Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion .
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Cat. No.: HY-P2185A
Target:  

MMP

Research Areas:  

Others

NFF-3 TFA, the peptide, is a selective MMP substrate. NFF-3 TFA selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 TFA is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 TFA with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity .
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Cat. No.: HY-114363
CAS No.: 1832686-43-7
Target:  

c-Met/HGFR

Research Areas:  

Cancer

SRI 31215 is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC50 values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer .
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Cat. No.: HY-P2185
CAS No.: 158584-09-9
Target:  

MMP

Research Areas:  

Others

NFF-3, the peptide, is a selective MMP substrate. NFF-3 selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity .
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Cat. No.: HY-P76380
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HGFAC; Serine Protease HGFAC; HGF activator; HGFA Serine Protease; HGFA; HGFAP; hepatocyte growth factor activator Serine Protease; hepatocyte growth factor activator
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77960
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: HGFAC; Serine Protease HGFAC; HGF activator; HGFA Serine Protease; HGFA; HGFAP; hepatocyte growth factor activator Serine Protease; hepatocyte growth factor activator
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P700734
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HGFAC; Serine Protease HGFAC; HGF activator; HGFA Serine Protease; HGFA; HGFAP; hepatocyte growth factor activator Serine Protease; hepatocyte growth factor activator
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P70202
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPINT2; hepatocyte growth factor activator Inhibitor-2; Serine Peptidase Inhibitor, Kunitz Type 2; Serine Protease Inhibitor, Kunitz Type, 2; HAI-2; HGF activator Inhibitor 2; HAI2; Placental Bikunin; hepatocyte growth factor activator Inhibitor Type 2; T
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76964
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPINT2; hepatocyte growth factor activator Inhibitor-2; Serine Peptidase Inhibitor, Kunitz Type 2; Serine Protease Inhibitor, Kunitz Type, 2; HAI-2; HGF activator Inhibitor 2; HAI2; Placental Bikunin; hepatocyte growth factor activator Inhibitor Type 2; T
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P73091
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPINT1; MANSC2; Serine Peptidase Inhibitor, Kunitz Type 1; HAI; HAI-1; Serine Protease Inhibitor, Kunitz Type 1; hepatocyte growth factor activator Inhibitor Type 1; HAI1; Kunitz-Type Protease Inhibitor 1
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P73092
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPINT1; MANSC2; Serine Peptidase Inhibitor, Kunitz Type 1; HAI; HAI-1; Serine Protease Inhibitor, Kunitz Type 1; hepatocyte growth factor activator Inhibitor Type 1; HAI1; Kunitz-Type Protease Inhibitor 1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P705239
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPINT1; MANSC2; Serine Peptidase Inhibitor, Kunitz Type 1; HAI; HAI-1; Serine Protease Inhibitor, Kunitz Type 1; hepatocyte growth factor activator Inhibitor Type 1; HAI1; Kunitz-Type Protease Inhibitor 1
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705271
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPINT1; MANSC2; Serine Peptidase Inhibitor, Kunitz Type 1; HAI; HAI-1; Serine Protease Inhibitor, Kunitz Type 1; hepatocyte growth factor activator Inhibitor Type 1; HAI1; Kunitz-Type Protease Inhibitor 1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-187994
Research Areas:  

Metabolic Disease

Antifibrotic agent 4 is an antifibrotic agent. Antifibrotic agent 4 inhibits the expression of the fibrotic markers α-SMA and COL1A1 in hepatic stellate cells by binding to FGFR4 and reducing its autophosphorylation, ameliorates liver injury and collagen deposition in mouse models of liver fibrosis, and does not inhibit the hERG potassium channel. Antifibrotic agent 4 can be used in the research of liver fibrosis .
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