6 Results for "

human lymphoma Raji cells

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "human lymphoma Raji cells" in MCE Product Catalog:

Cat. No.: HY-156249
CAS No.: 1466546-45-1
NMS-P528 is a DNA minor groove alkylating agent and ADC payload. NMS-P528 undergoes intramolecular cyclization to form reactive electrophilic derivatives, which in turn induce DNA damage, cell cycle arrest, and Apoptosis. NMS-P528 shows no significant anti-tumor activity as a free payload in a HER2-negative Raji lymphoma mouse xenograft model. NMS-P528 serves as the cytotoxic payload for the antibody-drug conjugate EV20/NMS-P945. NMS-P528 can be used in research related to breast cancer, gastric cancer, colon adenocarcinoma, Burkitt's lymphoma, neuroblastoma, pancreatic cancer, prostate cancer, head and neck cancer, ovarian cancer, and melanoma .
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Cat. No.: HY-187813
Target:  

HDAC

Research Areas:  

Cancer

HDAC2-IN-4 is a HDAC2 inhibitor with an IC50 of 4.2 nM against human HDAC2. HDAC2-IN-4 binds to the active site of HDAC2 via hydrogen bonding and hydrophobic interactions, forming a thermodynamically stable and kinetically compatible protein-ligand complex to inhibit enzymatic activity. HDAC2-IN-4 inhibits cancer cell proliferation and exhibits low toxicity to normal cells. HDAC2-IN-4 can be used in studies related to human endocervical adenocarcinoma and Burkitt lymphoma .
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Cat. No.: HY-P992176
Target:  

CD47

Research Areas:  

Cancer

ADU-1805 is a humanized monoclonal IgG2 antibody, a selective, pan-allelic anti-SIRPα antibody, with a Kd value of 11.0 × 10 -9 M for hSIRPαV1. ADU-1805 binds to all known hSIRPα alleles. ADU-1805 blocks the SIRPα-CD47 interaction, promotes phagocytosis of cells, and enhances trogocytosis of cells. ADU-1805 can be used in research related to Burkitt lymphoma .
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Cat. No.: HY-P991902

Target:  

CD20

Research Areas:  

Cancer

NAV006 is an anti-CD20 antibody variant of Rituximab (HY-P9913) with a Kd of 30.5 nM to CD20. NAV006 exhibits reduced interaction with CA125 and demonstrates enhanced antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) activity. NAV006 displays antitumor activity against lymphoma and can be used in research on non-Hodgkin lymphoma .
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Cat. No.: HY-P992211

Target:  

Fc Receptor (FcR)

Research Areas:  

Cancer

Anti-CD32b/FCGR2B Antibody (2B6) is a human monoclonal antibody targeting CD32B. Anti-CD32b/FCGR2B Antibody (2B6) can be used for research on B-cell lymphoma .
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Cat. No.: HY-P991935

Target:  

Apoptosis

Research Areas:  

Cancer

ANT1034 is humanized anti-CD52 antibody. ANT1034 directs antibody dependent and complement dependent cell cytotoxicity, induces Apoptosis when cross-linked or in the presence of a cross-linking antibody. ANT1034 leads to increased survival in a SCID CD52 tumour xenograft model. ANT1034 can be used for the research of B cell malignancies .
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