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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
human polo-like kinase 1
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "human polo-like kinase 1" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P76550
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLK1; STPK13; Prev. PLK; Cell Cycle Regulated Protein kinase; Serine/Threonine-Protein kinase PLK1; polo-like kinase (Drosophila); polo-like kinase 1; polo (Drosophia)-like kinase; Serine/Threonine-Protein kinase 13; polo like kinase 1; PLK-1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705858
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLK1; STPK13; Prev. PLK; Cell Cycle Regulated Protein kinase; Serine/Threonine-Protein kinase PLK1; polo-like kinase (Drosophila); polo-like kinase 1; polo (Drosophia)-like kinase; Serine/Threonine-Protein kinase 13; polo like kinase 1; PLK-1
Species:
Human
Source:
E. coli
Cat. No.: HY-P705859
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLK1; STPK13; Prev. PLK; Cell Cycle Regulated Protein kinase; Serine/Threonine-Protein kinase PLK1; polo-like kinase (Drosophila); polo-like kinase 1; polo (Drosophia)-like kinase; Serine/Threonine-Protein kinase 13; polo like kinase 1; PLK-1
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-187593
CAS No.: 1186496-84-3
Target:
Research Areas:
PLHSpT is an inhibitor of the Polo-box domain (PBD) of Polo-like kinase 1 (Plk1), with an IC50 of 36 μM. It binds to the PB1-PB2 cleft of the Plk1 PBD to block its interaction with phosphoprotein substrates, thereby inducing mitotic arrest and apoptosis in tumor cells. PLHSpT exerts antiglioma effects when delivered via liposomes, and it is applicable to research on glioblastoma multiforme and other human cancers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
