9 Results for "

hyperglycaemia

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "hyperglycaemia" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-19618
CAS No.: 1550053-02-5
Target:  

HDAC HIV Apoptosis

Research Areas:  

Infection Metabolic Disease

BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23-fold selectivity for HDAC3 over HDAC1 (IC50 of 1.26 μM) or HDAC2 (IC50 of 1.34 μM). BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. BRD3308 activates HIV-1 transcription and disrupts HIV-1 latency .
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Cat. No.: HY-12525
CAS No.: 1207989-09-0
Purity:  ≥98.0%
Target:  

GCGR

Research Areas:  

Metabolic Disease

LGD-6972 is a selective and orally active glucagon receptor antagonist. LGD-6972 has the potential for type 2 diabetes research .
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Cat. No.: HY-109530
CAS No.: 133107-64-9
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin lispro is a recombinant human insulin analogue and is one of three rapid-acting insulin analogues available. Insulin lispro can be used for the research of hyperglycaemia in diabetes mellitus .
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Cat. No.: HY-126221A
CAS No.: 98063-21-9
Purity:  99.95%
Synonyms: Emeriamine
Research Areas:  

Metabolic Disease

(R)-Aminocarnitine (Emeriamine) is a fatty acid oxidation inhibitor. (R)-Aminocarnitine reduces hyperglycaemia and ketosis. (R)-Aminocarnitine can be used in the study of metabolic diseases .
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Cat. No.: HY-P99867
CAS No.: 1204390-13-5
Synonyms: MEDI 573

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Dusigitumab is a fully human IgG2λ monoclonal antibody that targets IGF-1 and IGF-2 with picomolar binding affinity. Dusigitumab blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R as well as activation of IR-A, thereby inhibiting the activation of downstream signaling pathways. Dusigitumab is applicable to research related to advanced solid tumors and hormone receptor-positive metastatic breast cancer .
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Cat. No.: HY-108614
CAS No.: 918902-32-6
Target:  

Phosphorylase

Research Areas:  

Metabolic Disease

GPi688 is a potent and orally active glycogen phosphorylase (GPa) inhibitor with IC50s of 19 nM, 61 nM and 12 nM for human liver GPa, rat liver GPa and human skeletal muscle GPa, respectively . GPi688 can inhibit glucagons-mediated glucose output in rat primary hepatocytes. GPi688 can be used for researching glucagon-mediated hyperglycaemia .
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Cat. No.: HY-12525A
CAS No.: 1207989-22-7
Target:  

GCGR

Research Areas:  

Metabolic Disease

LGD-6972 sodium is a selective and orally active glucagon receptor antagonist. LGD-6972 sodium has the potential for type 2 diabetes research .
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Cat. No.: HY-12525B
Target:  

GCGR

Research Areas:  

Metabolic Disease

LGD-6972 ammonium is a selective and orally active glucagon receptor antagonist. LGD-6972 ammonium has the potential for type 2 diabetes research .
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Cat. No.: HY-42680A
CAS No.: 17598-81-1
Research Areas:  

Metabolic Disease

Tagatose is a low-calorie sugar substitute. Tagatose exhibits beneficial effects on postprandial hyperglycaemia and hyperinsulinaemia. Tagatose can induce weight loss and raise high-density lipoprotein cholesterol. Tagatose has antioxidant activity. Tagatose can be studied in research on type 2 diabetes and obesity .
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