2 Results for "

hypusination

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "hypusination" in MCE Product Catalog:

1
9''-Methyl salvianolate B
9''-Methyl salvianolate B
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1 Cited Publications
Cat. No.: HY-N2397
CAS No.: 1167424-31-8
Synonyms: MSB
Category:  

Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Metabolic Disease Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields

Target:  

DNA/RNA Synthesis PPAR NF-κB Autophagy

9''-Methyl salvianolate B (MSB) is a blood-brain barrier-permeable inhibitor with high affinity for g5Rp, with a Kd value of 117 nM against African swine fever virus (ASFV) g5Rp. 9''-Methyl salvianolate B also acts as a ZBP1 inhibitor. It exhibits strong binding affinity to key proteins in the PPARγ/NF-κB pathway. 9''-Methyl salvianolate B blocks the interaction between ASFV g5Rp and host proteins eIF5A or RPS15. It restores hypusination modification of eIF5A, promotes autophagy (Autophagy), and inhibits ASFV replication. 9''-Methyl salvianolate B effectively disrupts ZBP1-mediated PANoptosome assembly. It effectively alleviates myocardial ischemia/reperfusion injury. 9''-Methyl salvianolate B can be used in studies related to African swine fever .
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VT00065
VT00065
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Cat. No.: HY-W141446
CAS No.: 144163-68-8
Target:  

Eukaryotic Initiation Factor (eIF)

Research Areas:  

Others

VT00065 is a covalent DHS inhibitor. VT00065 forms a redox-dependent covalent bond with the catalytic lysine K329 of DHS, locking the enzyme in an inactive state .
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