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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
lyso-Gb
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "lyso-Gb" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N7745
CAS No.: 52050-17-6
Synonyms: Glucopsychosine; lyso-Gb1; lyso-GL1
Target:
2
Target:
Research Areas:
Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
Cat. No.: HY-N12408
CAS No.: 126550-86-5
Synonyms: lyso-Gb3; lyso-GL3
Target:
Cat. No.: HY-N7745S
CAS No.: 2315262-29-2
Synonyms: Glucopsychosine-d7; lyso-Gb1-d7; lyso-GL1-d7
Cat. No.: HY-N7745S1
Synonyms: Glucopsychosine-d5; lyso-Gb1-d5; lyso-GL1-d5
Cat. No.: HY-N7745S2
CAS No.: 299172-48-8
Synonyms: Glucopsychosine-13C6; lyso-Gb1-13C6; lyso-GL1-13C6
Cat. No.: HY-14929
CAS No.: 108147-54-2
Synonyms: GR181413A free base; 1-Deoxygalactonojirimycin
Target:
Research Areas:
Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
