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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
metabolic acidosis
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "metabolic acidosis" in MCE Product Catalog:
62
62 Publications Verification
Cat. No.: HY-Y1269
CAS No.: 12125-02-9
62
62 Publications Verification
Cat. No.: HY-Y1269C
CAS No.: 12125-02-9
Synonyms: Salmiac, for cell culture
Cat. No.: HY-Y1269S
CAS No.: 39466-62-1
Target:
Research Areas:
Ammonium chloride- 15N is the 15N labeled Ammonium chloride (HY-Y1269). Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor .
Synonyms: (R)-2-Hydroxypropionic acid sodium
Target:
Cat. No.: HY-Y1269AS
CAS No.: 12015-14-4
Cat. No.: HY-Y1269I
CAS No.: 12125-02-9
Synonyms: Salmiac (Pharmaceutical primary standard, USP)
Cat. No.: HY-111095BR
CAS No.: 920-49-0
Synonyms: (R)-2-Hydroxypropionic acid sodium (Standard)
Cat. No.: HY-FL0002
Synonyms: Bicarbonate Ringer's solution
Research Areas:
Sodium bicarbonate ringer's solution is a solution containing sodium bicarbonate and electrolytes such as sodium, magnesium, potassium, calcium and chloride, which can be used as a cell integrity protectant. It is used to replenish and correct extracellular fluid and to treat metabolic acidosis.
Cat. No.: HY-L204
582 compounds
Lactic acid metabolism is one of the key metabolic pathways within living organisms. It plays a crucial role not only in cellular energy conversion but is also closely related to a variety of physiological and pathological processes. The production and clearance of lactic acid are important indicators of cellular metabolic balance, and its abnormal regulation may lead to conditions such as lactic acidosis, muscle fatigue, and hereditary metabolic diseases. Moreover, lactic acid is closely related to the malignancy of tumors and is considered a biomarker for malignant tumors and poor prognosis. Lactic acid can serve as a metabolic substrate to support the metabolic needs of tumor cells under hypoxic conditions, and it can also cause acidification of the tumor microenvironment, suppress immune cell function to promote immune evasion, and induce drug resistance in tumor cells. Currently, targeting lactic acid-lactylation and its related metabolic pathways has become a new research avenue for cancer treatment. In-depth exploration of the molecular mechanisms of lactic acid metabolism can help in screening lead compounds that regulate the lactic acid metabolism.
MCE contains 582 small molecule compounds targeting enzymes involved in lactic acid metabolism. This library is of significant value for researching the role of lactate metabolism in the mechanisms of diseases.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
