9 Results for "

neoantigens

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "neoantigens" in MCE Product Catalog:

Cat. No.: HY-P11058
CAS No.: 355012-70-3
Synonyms: OVAp
Target:  

MHC

Research Areas:  

Cancer

OVA(250-264) (OVAvac) (OVAp) is an antigen peptide that can be from ovalbumin (OVA) presented by the class I MHC molecule, H-2Kb. OVA(250-264) combined withαMSLN (anti-MSLN antibody) significantly induces antigen-specific CD8 + T cell generation and infiltration for enhancing antitumor efficacy in orthotopic pancreatic cancer mice model. OVA(250-264) can be used for neoantigen vaccine development in pancreatic cancer immunotherapy research .
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Cat. No.: HY-P3487
CAS No.: 1223335-84-9
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

GAGGVGKSA is a wild type KRAS G12D 9mer peptide. GAGGVGKSA can be used as an immunogenic neoantigen for cancer immunotherapy research .
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Cat. No.: HY-P11060
Synonyms: Adpgk peptide
Target:  

MHC

Research Areas:  

Cancer

MC38 SLP Adpgk (Adpgk peptide) is an H-2 K b-restricted colorectal cancer neoantigen peptide. MC38 SLP Adpgk is formulated into PCNP nanocomplexes together with CpG ODN. PCNP vaccines significantly enhance the co-delivery efficiency of neoantigens and adjuvants to lymphoid organs, and activate cytotoxic T cells. PCNP vaccines not only protect mice from MC-38 colorectal tumor invasion, but also exhibit anti-tumor efficacy in established colorectal tumor models and significantly prolong the survival of tumor-bearing mice .
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Cat. No.: HY-139907B
Purity:  99.60%
DG013A formate is a zinc-dependent M1-aminopeptidase inhibitor that exhibits inhibitory activity against ERAP1 (IC50 = 33 nM) and ERAP2 (IC50 = 11 nM). DG013A formate enhances SRHFLAFSFR epitope presentation, rescues GSW11 peptide neoantigen presentation, reduces SIINFEKL presentation, modulates the immunopeptidome, decreases HLA-B27 free heavy chain expression, and reduces IL-17A secretion. DG013A formate exhibits antiproliferative activity. DG013A formate can be used for research on autoimmune diseases and melanoma .
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Cat. No.: HY-P3488
CAS No.: 2032119-68-7
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

GADGVGKSA is a mutant KRAS G12D 9mer peptide. GADGVGKSA can be used as an immunogenic neoantigen for cancer immunotherapy research .
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Cat. No.: HY-P3486
CAS No.: 199477-24-2
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

GADGVGKSAL is a mutant KRAS G12D 10mer peptide. GADGVGKSAL can be used as an immunogenic neoantigen for cancer immunotherapy research .
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Cat. No.: HY-139907
CAS No.: 2007955-07-7
DG013A is a zinc-dependent M1-aminopeptidase inhibitor that exhibits inhibitory activity against ERAP1 (IC50 = 33 nM) and ERAP2 (IC50 = 11 nM). DG013A enhances SRHFLAFSFR epitope presentation, rescues GSW11 peptide neoantigen presentation, reduces SIINFEKL presentation, modulates the immunopeptidome, decreases HLA-B27 free heavy chain expression, and reduces IL-17A secretion. DG013A exhibits antiproliferative activity. DG013A can be used for research on autoimmune diseases and melanoma .
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Cat. No.: HY-175604
CAS No.: 1061105-16-5
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

SCL-1 is an orally active anti-PD-1/PD-L1 inhibitor. SCL-1 can inhibit PD-1/PD-L1 binding. SCL-1 increases T cells, B cells and natural killer cells. SCL-1 exerts strong tumor growth inhibitory effects that were mediated by effector T-cell induction inside tumors and the up-regulated expression of long non-coding RNAs as neoantigens leading to cytotoxic T lymphocyte activation. SCL-1 can be used for the research of cancer, such as triple-negative breast cancer .
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Cat. No.: HY-P11059
Synonyms: Reps1 peptide
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

MC38 SLP Reps1 is a peptide neoantigen generated by mutation of the MC38 colon cancer cell line and can be used for the synthesis of nanoparticle vaccines .
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