41 Results for "

neonatal Fc receptor

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "neonatal Fc receptor" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99804
CAS No.: 2429913-18-6
Synonyms: MK1654

Target:  

RSV

Research Areas:  

Infection

Clesrovimab (MK1654) is a humanized IgG1 monoclonal antibody targeting the respiratory syncytial virus (RSV) protein F. Clesrovimab binds to pre-fusion and post-fusion forms of RSV-A fusion protein with high affinity, with corresponding KD values of 71 pM and 480 pM, respectively. Clesrovimab is applicable for the research of RSV infection .
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2
2 Cited Publications
Cat. No.: HY-P9979
CAS No.: 1584645-37-3
Synonyms: UCB7665

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Rozanolixizumab (UCB7665), a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P), is used to the research of reducing pathogenic IgG in autoimmune and alloimmune diseases .
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1
1 Cited Publications
Cat. No.: HY-P70601
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal Fragment Crystallizable Fc receptor FcRn; IgG Fc Fragment receptor Transporter Alpha Chain; Immunoglobulin receptor, Intestinal, Heavy Chain; IgG receptor FcRn Large Subunit P51; neonatal Fc-receptor For Ig; FcgammaRn; FcRN Alpha-Chain; Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc receptor; FcRn Alpha Chain; Transmembrane Alpha Chain Of The neonatal receptor; Alpha-Chain; Fc Fragment Of IgG, receptor, Transporter, Alpha; FcRN; Fc Fragment Of IgG receptor And Transporter; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P990091
CAS No.: 2756228-76-7
Synonyms: SAR 445088
Riliprubart (SAR 445088) is a selective anti-C1s humanized IgG4 monoclonal antibody with mutations that enhance its binding to the neonatal Fc receptor. Riliprubart blocks activation of the classical complement pathway, prevents the formation of the C3 convertase C4b2a, and inhibits complement-mediated hemolytic activity. Riliprubart can be used in research related to classical complement-mediated diseases, cold agglutinin disease, and chronic inflammatory demyelinating polyneuropathy. For the isotype control of Riliprubart, refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P991055
CAS No.: 2649379-96-2
Synonyms: RG-6234; RO-7425781

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-145775
CAS No.: 1425051-22-4
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

hIgG-hFc receptor-IN-1 is a quinoxaline-based human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction inhibitor with an IC50 of 2 μM. hIgG-hFc receptor-IN-1 blocks the binding of hIgG to human FcRn. hIgG-hFc receptor-IN-1 can be used for immune-related research .
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Cat. No.: HY-P704603
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704604
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P704606
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P70656
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-187394
CAS No.: 1425050-80-1
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

hIgG-hFc receptor-IN-3 is a protein-protein interaction inhibitor of human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn). Identified via virtual ligand screening and optimized through structure-activity relationship studies, hIgG-hFc receptor-IN-3 competitively inhibits the binding of IgG to FcRn, thereby accelerating the clearance of endogenous IgG. hIgG-hFc receptor-IN-3 can be used for the research of autoimmune diseases .
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Cat. No.: HY-P11882
CAS No.: 947545-69-9
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1436 is a selective human neonatal Fc receptor (hFcRn) antagonist with an IC50 of 2.4 nM. SYN1436 binds to hFcRn and inhibits hFcRn-hIgG interaction. SYN1436 can be used for the research of autoimmune diseases .
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Cat. No.: HY-P72192
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P705914
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P72368
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal Fragment Crystallizable Fc receptor FcRn; IgG Fc Fragment receptor Transporter Alpha Chain; Immunoglobulin receptor, Intestinal, Heavy Chain; IgG receptor FcRn Large Subunit P51; neonatal Fc-receptor For Ig; FcgammaRn; FcRN Alpha-Chain; Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc receptor; FcRn Alpha Chain; Transmembrane Alpha Chain Of The neonatal receptor; Alpha-Chain; Fc Fragment Of IgG, receptor, Transporter, Alpha; FcRN; Fc Fragment Of IgG receptor And Transporter; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P11786
CAS No.: 1020264-43-0
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1327 is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 can be used in studies related to IgG-mediated autoimmune diseases .
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Cat. No.: HY-P11786A
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1327 acetate is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 acetate competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acetate acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 acetate can be used in studies related to IgG-mediated autoimmune diseases .
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Cat. No.: HY-P71664
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P73522
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76920
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; neonatal Crystallizable Fc receptor FcRn Splice Variant 6; neonatal Fc receptor; neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; neonatal
Species:  
Cynomolgus
Source:  
HEK293
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