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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
nephroblastoma
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "nephroblastoma" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-N2445
CAS No.: 37308-75-1
Cat. No.: HY-169093
CAS No.: 2768610-97-3
Target:
Research Areas:
MS41 is a ENL PROTAC degrader with a DC50 of 3.50 nM. MS41 recruits the VHL E3 ubiquitin ligase, triggers ENL degradation via the ubiquitin-proteasome system, and simultaneously induces AF9 degradation. MS41 reduces the chromatin occupancy of ENL-associated transcription elongation complexes, suppresses oncogene expression, and activates differentiation gene expression. MS41 inhibits leukemia cell growth and induces cell cycle arrest and apoptosis. MS41 inhibits leukemia progression in xenograft mouse models. MS41 can be used for research on mixed lineage leukemia-rearranged leukemia and nephroblastoma .
Cat. No.: HY-162536
Target:
Research Areas:
Pan-RAS-IN-5 is a macrocyclic pan-RAS inhibitor that targets mutant RAS (including KRAS, NRAS, and HRAS). Pan-RAS-IN-5 inhibits the proliferation of various KRAS-mutant cancer cells. Pan-RAS-IN-5 is applicable to the research of KRAS mutation-related cancers such as pancreatic cancer, nephroblastoma, and colon adenocarcinoma .
Cat. No.: HY-P71149
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCN3; Protein NOV Homolog; Prev. NOV; IBP-9; IGFBP9; nephroblastoma-Overexpressed Gene Protein Homolog; Nephro Blastoma-Overexpressed Gene Protein Homolog; nephroblastoma Overexpressed Gene; Insulin-Like Growth Factor-Binding Protein 9; NOVh; Nephroblasto
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76520
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN3; Protein NOV Homolog; Prev. NOV; IBP-9; IGFBP9; nephroblastoma-Overexpressed Gene Protein Homolog; Nephro Blastoma-Overexpressed Gene Protein Homolog; nephroblastoma Overexpressed Gene; Insulin-Like Growth Factor-Binding Protein 9; NOVh; Nephroblasto
Species:
Canine
Source:
HEK293
Cat. No.: HY-P701327
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN3; Protein NOV Homolog; Prev. NOV; IBP-9; IGFBP9; nephroblastoma-Overexpressed Gene Protein Homolog; Nephro Blastoma-Overexpressed Gene Protein Homolog; nephroblastoma Overexpressed Gene; Insulin-Like Growth Factor-Binding Protein 9; NOVh; Nephroblasto
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P77454
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CCN3; Protein NOV Homolog; Prev. NOV; IBP-9; IGFBP9; nephroblastoma-Overexpressed Gene Protein Homolog; Nephro Blastoma-Overexpressed Gene Protein Homolog; nephroblastoma Overexpressed Gene; Insulin-Like Growth Factor-Binding Protein 9; NOVh; Nephroblasto
Species:
Rhesus Macaque
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
