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Results for "

oncostatin M (OSM)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) DNA/RNA Synthesis (2) FABP (1) Interleukin Related (7) PPAR (1) Reference Standards (1) STAT (3)
By Research Areas:	Cancer (7) Inflammation/Immunology (5)
Oligonucleotides:	Aptamers (2)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-33354

Nitrochin 3 Publications Verification 4-NQO	DNA/RNA Synthesis Apoptosis	Inflammation/Immunology Cancer
Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway .

HY-P99519

Vixarelimab 1 Publications Verification KPL-716	Interleukin Related	Inflammation/Immunology
Vixarelimab (KPL-716) is a human *anti-oncostatin* M (OSM) receptor β subunit monoclonal antibody. Vixarelimab inhibits IL-31** and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash .

HY-175465

SMI-10B13	Interleukin Related STAT	Cancer
SMI-10B13 is an Oncostatin M (OSM) inhibitor with a K_D of 6.6 μM. SMI-10B13 inhibits OSM-mediated STAT3 phosphorylation in T47D and MCF-7 cell lines (IC₅₀ = 136 and 164 nM, respectively). SMI-10B13 shows anti-tumor effect in human breast cancer mice models .

HY-148692

OSM-SMI-10B	STAT	Cancer
OSM-SMI-10B a derivative of OSM-SMI-10. OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M) .

HY-113790

ISX-1	PPAR FABP	Others
ISX-1 is an isoxazole. ISX-1 has anti-adipogenic and pro-osteogenic activities. ISX-1 can be used for the research of osteopenia and osteoporosis .

HY-148693

OSM-SMI-8 NSC642624	Interleukin Related	Cancer
OSM-SMI-8 (NSC642624) is a potent OSM (oncostatin M) antagonist. OSM-SMI-8 has the potential for the research of cancer .

HY-P991051

GSK-2330811	Interleukin Related	Inflammation/Immunology
GSK-2330811 is a humanized IgG1 antibody that targets *Oncostatin M (OSM)*. GSK-2330811 has the potential for the study of diffuse cutaneous systemic sclerosis (dcSSc). The isotype control for GSK-2330811 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-148695B

ADR58 sodium	Interleukin Related	Inflammation/Immunology
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

HY-148693A

(E/Z)-OSM-SMI-8 (E/Z)-NSC642624	Interleukin Related	Cancer
(E/Z)-OSM-SMI-8 is the racemate of OSM-SMI-8 (HY-148693). OSM-SMI-8 is the antagonist for *OSM* (oncostatin M), that exhibits the potential in anti-cancer research .

HY-148692A

(E/Z)-OSM-SMI-10B	STAT	Cancer
(E/Z)-OSM-SMI-10B a derivative of OSM-SMI-10. (E/Z)-OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M) .

HY-148695C

Truncated ADR58 sodium	Interleukin Related	Inflammation/Immunology
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

HY-33354R

Nitrochin (Standard) 4-NQO (Standard)	DNA/RNA Synthesis Apoptosis Reference Standards	Cancer
Nitrochin (Standard) is the analytical standard of Nitrochin. This product is intended for research and analytical applications. Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway .

Cat. No.	상품명	Target	Research Area	Image

HY-P99519

Vixarelimab 1 Publications Verification KPL-716	Interleukin Related	Inflammation/Immunology
Vixarelimab (KPL-716) is a human *anti-oncostatin* M (OSM) receptor β subunit monoclonal antibody. Vixarelimab inhibits IL-31** and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash .

HY-P991051

GSK-2330811	Interleukin Related	Inflammation/Immunology
GSK-2330811 is a humanized IgG1 antibody that targets *Oncostatin M (OSM)*. GSK-2330811 has the potential for the study of diffuse cutaneous systemic sclerosis (dcSSc). The isotype control for GSK-2330811 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .

Species:	Human (6) Mouse (3) Cynomolgus (1) Canine (1)
Tag:	His (8) Tag Free (3) Avi (2)
Source:	HEK293 (8) E. coli (3)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P700805

	OSM Protein, Mouse (HEK293, His) oncostatin M; OSM; MGC20461; oncostatin-M	Mouse	HEK293
	OSM protein is a multifunctional growth regulator that effectively inhibits the proliferation of tumor cell lines and regulates the production of cytokines, including IL-6, G-CSF, and GM-CSF produced by endothelial cells.It specifically binds to type II OSM receptors, forming a heterodimer composed of OSMR and IL6ST.OSM Protein, Mouse (HEK293, His) is the recombinant mouse-derived OSM protein, expressed by HEK293 , with C-His labeled tag.

HY-P70465

	OSM Protein, Human (His) 4 Publications Verification oncostatin-M; OSM	Human	E. coli
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (His) is the recombinant human-derived OSM protein, expressed by E. coli , with N-6*His labeled tag.

HY-P74662

	OSM Protein, Human (HEK293) oncostatin M; OSM	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (HEK293) is the recombinant human-derived OSM protein, expressed by HEK293 , with tag free.

HY-P70465G

	GMP OSM Protein, Human (His) oncostatin-M; OSM	Human	E. coli
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. GMP OSM Protein, Human (His) is the recombinant human-derived OSM protein, expressed by E. coli , with N-6*His labeled tag.

HY-P73331

	OSM Protein, Human (HEK293, His) oncostatin M; OSM	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (HEK293, His) is the recombinant human-derived OSM protein, expressed by HEK293 , with C-His labeled tag.

HY-P703730

	OSM Protein, Cynomolgus (HEK293, His) oncostatin M; OSM	Cynomolgus	HEK293
	OSM Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Oncostatin M/OSM protein, expressed by HEK293, with C-His tag.

HY-P7275

	OSM Protein, Mouse 1 Publications Verification rMuOSM; oncostatin-M	Mouse	E. coli
	OSM Protein, Mouse is a gp130 cytokine family member, shows homeostatic and proinflammatory activities and can modify extracellular matrix.

HY-P7274

	OSM Protein, Mouse (HEK293) 1 Publications Verification rMuOSM; oncostatin-M	Mouse	HEK293
	OSM Protein, Mouse (HEK293) is a gp130 cytokine family member, shows homeostatic and proinflammatory activities and can modify extracellular matrix.

HY-P78502

	OSM Protein, Human (HEK293, His-Avi) oncostatin M; OSM; MGC20461	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (HEK293, His-Avi) is the recombinant human-derived OSM protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P703755

	OSM Protein Protein, Canine (HEK293, His) oncostatin M; OSM; MGC20461	Canine	HEK293
	OSM is a glycoprotein belonging to the interleukin-6 family of cytokines that can inhibit the growth of cells from melanoma and other solid tumors. OSM Protein Protein, Canine (HEK293, His) is the recombinant canine-derived Oncostatin M/OSM protein, expressed by HEK293, with C-His tag.

HY-P78187

	OSM Protein, Human (Biotinylated, HEK293, His-Avi) oncostatin M; OSM; MGC20461	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived OSM protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

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HY-P83068

	Oncostatin M Antibody (YA2813) oncostatin-M (OSM)	WB	Human, Mouse, Rat
	Oncostatin M Antibody (YA2813) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Oncostatin M.

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Cat. No.	상품명		Classification

HY-148695B

ADR58 sodium		Aptamers
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

HY-148695C

Truncated ADR58 sodium		Aptamers
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

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