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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
osteoblastic
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "osteoblastic" in MCE Product Catalog:
201
201 Publications Verification
XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation .
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6 Cited Publications
Synonyms: p-Tolyl sulfate potassium
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
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4 Cited Publications
Synonyms: Hexadecadrol (GMP); Prednisolone F (GMP)
3
3 Cited Publications
Cat. No.: HY-N2532
CAS No.: 22055-22-7
Category:
Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Plants Infection Monophenols Phenols Phenylpropanoids Berberidaceae Disease Research Fields Inflammation/Immunology
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3
3 Cited Publications
Cat. No.: HY-P1252
CAS No.: 12583-68-5
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Metabolic Disease Agavaceae Plants Agave sisalana Perr. ex Engelm. Disease Research Fields Steroids
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Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM . Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca 2+ transport with an IC50 of 140 nM in a Ca 2+ uptake assay . Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway . Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease .
Cat. No.: HY-N6663
CAS No.: 13466-78-9
Category:
Other Monoterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-109569
CAS No.: 11032-49-8
Category:
Other Terpenoids Terpenoids Metabolic Disease Endogenous metabolite Disease Research Fields
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Cat. No.: HY-124588
CAS No.: 1535187-91-7
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MC3343, a DNMT inhibitor (EC50 of 5.7 μM) and a strong DNA binder, affects tumor proliferation by blocking OS cells in G1 or G2/M phases and induces osteoblastic differentiation through the specific re-expression of genes regulating this physiological process .
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SC-19220 is a prostaglandin E2 receptor EP1 antagonist. SC-19220 blocks functional EP1 receptor activation, and RANK/RANKL signaling pathway. SC-19220 inhibits osteoclast formation and bone resorption by pre-existing osteoclasts. SC-19220 can be used for the research of osteoporotic disorders, inflammatory bone resorption .
Cat. No.: HY-N11038
CAS No.: 1507388-29-5
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Cat. No.: HY-15147R
CAS No.: 284028-89-3
XAV-939 (Standard) is the analytical standard of XAV-939. This product is intended for research and analytical applications. XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation .
Cat. No.: HY-N4299
CAS No.: 1913319-59-1
Cat. No.: HY-N7503R
CAS No.: 905954-17-8
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Cat. No.: HY-N6663R
CAS No.: 13466-78-9
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Cat. No.: HY-P1252A
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Cat. No.: HY-N17565
CAS No.: 1242514-92-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
