12 Results for "

osteoblastic cells

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "osteoblastic cells" in MCE Product Catalog:

6
6 Cited Publications
製品番号: HY-111431A
CAS 番号: 91978-69-7
純度:  99.92%
別名: p-Tolyl sulfate potassium
p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .
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製品番号: HY-122808
CAS 番号: 560-09-8
純度:  ≥98.0%
(-)-Camphoric acid is the less active enantiomer of Camphoric acid. Camphoric acid induces glutamate receptor expression. Camphoric acid also significantly induces the activation of NF-κB and AP-1. Camphoric acid significantly stimulates the differentiation of mouse osteoblastic MC3T3-E1 subclone 4 cells. Camphoric acid has weak regulatory function towards glutamate receptors. Camphoric acid can induce mRNA expression of glutamate signaling molecules and activate transcription factors, thereby stimulating osteoblast differentiation .
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製品番号: HY-N1403
CAS 番号: 77-60-1
Tigogenin is a steroidal sapogenins. Tigogenin can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin can inhibit cells proliferation and induce apoptosis. Tigogenin can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .
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製品番号: HY-108464A
CAS 番号: 1161-94-0
純度:  98.1%
Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM . Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca 2+ transport with an IC50 of 140 nM in a Ca 2+ uptake assay . Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway . Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease .
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製品番号: HY-109569
CAS 番号: 11032-49-8
Vitamin K2 is an orally active proliferation inhibitor. Vitamin K2 induces Autophagy and Apoptosis. Vitamin K2 reduces the levels of proinflammatory cytokines (such as IL-1β, TNF-α, and IL-6). Vitamin K2 inhibits cell growth in leukemia cells. Vitamin K2 can be used for the research of involutional osteoporosis, non-alcoholic fatty liver disease, ulcerative colitis, acute myeloid leukemia, myelodysplastic syndromes, and hepatocellular carcinoma .
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製品番号: HY-124588
CAS 番号: 1535187-91-7
Target:  

DNA Methyltransferase

研究分野:  

Cancer

MC3343, a DNMT inhibitor (EC50 of 5.7 μM) and a strong DNA binder, affects tumor proliferation by blocking OS cells in G1 or G2/M phases and induces osteoblastic differentiation through the specific re-expression of genes regulating this physiological process .
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製品番号: HY-102065
CAS 番号: 19395-87-0
純度:  99.71%
研究分野:  

Metabolic Disease

SC-19220 is a prostaglandin E2 receptor EP1 antagonist. SC-19220 blocks functional EP1 receptor activation, and RANK/RANKL signaling pathway. SC-19220 inhibits osteoclast formation and bone resorption by pre-existing osteoclasts. SC-19220 can be used for the research of osteoporotic disorders, inflammatory bone resorption .
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製品番号: HY-N11038
CAS 番号: 1507388-29-5
Drynachromoside A is a chromone glycoside. Drynachromoside A has biochemical effects on the osteoblastic (MC3T3-E1 cells) proliferation activities .
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製品番号: HY-N4299
CAS 番号: 1913319-59-1
Caesappanin C, a biphenyl dimer from the ethanolic extract of the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro. Caesappanin C has the potential to stimulate bone formation and regeneration . Caesappanin C can effectively deactivate HSV particles and bind HSV surface glycoprotein B (gB) to inhibit membrane fusion .
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製品番号: HY-N1403R
CAS 番号: 77-60-1
Tigogenin (Standard) is a steroidal sapogenins. Tigogenin (Standard) can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin (Standard) can inhibit cells proliferation and induce apoptosis. Tigogenin (Standard) can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .
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製品番号: HY-N17565
CAS 番号: 1242514-92-6
Category:  

Microorganisms Steroids

Target:  

Others

5a,9a-Epidioxy-8b,14b-epoxy-(22E)-ergosta-6,22-dien-3b-ol is a sterol that can be found in the edible mushroom Grifola gargal. 5a,9a-Epidioxy-8b,14b-epoxy-(22E)-ergosta-6,22-dien-3b-ol suppresses osteoclast formation without exhibiting cytotoxicity. 5a,9a-Epidioxy-8b,14b-epoxy-(22E)-ergosta-6,22-dien-3b-ol can be used for the research of osteoporosis .
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製品番号: HY-102065R
CAS 番号: 19395-87-0
SC-19220 (Standard) is the analytical standard of SC-19220 (HY-102065). This product is intended for research and analytical applications. SC-19220 is a prostaglandin E2 receptor EP1 antagonist. SC-19220 blocks functional EP1 receptor activation, and RANK/RANKL signaling pathway. SC-19220 inhibits osteoclast formation and bone resorption by pre-existing osteoclasts. SC-19220 can be used for the research of osteoporotic disorders, inflammatory bone resorption .
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