2 Results for "

p27Kip1 ubiquitination inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "p27Kip1 ubiquitination inhibitor" in MCE Product Catalog:

Cat. No.: HY-15301
CAS No.: 1319207-44-7
Purity:  99.03%
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27 Kip1, as confirmed by dose-response analysis.
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Cat. No.: HY-126757
CAS No.: 62462-98-0
Linichlorin A is a p27 Kip1 ubiquitination inhibitor that blocks p27 Kip1 degradation by inhibiting the Skp2-Cks1–p27 Kip1 interaction. Linichlorin A shows selective antiproliferative activity against tumor cells. Linichlorin A induces apoptosis in leukemia cells via cytochrome c release, caspase activation and PARP cleavage. Linichlorin A can be used in the study of leukemia, melanoma, cervical cancer and breast cancer .
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