39 Results for "

phthalate ester metabolite

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "phthalate ester metabolite" in MCE Product Catalog:

24
24 Publications Verification
Cat. No.: HY-W018392
CAS No.: 4376-20-9
Synonyms: MEHP; Phthalic acid mono-2-ethylhexyl ester
Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD) .
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5
5 Cited Publications
Cat. No.: HY-N7143
CAS No.: 131-70-4
Monobutyl phthalate is an orally active metabolite of Di-n-butyl phthalate (HY-Y0304) and an embryotoxic agent. Monobutyl phthalate regulates mesodermal lineage gene expression, inhibits uterine decidualization, reduces fetal testosterone levels without directly binding to the androgen receptor, and induces teratogenic effects during organogenesis. Monobutyl phthalate induces testicular oxidative stress and sperm abnormalities. Monobutyl phthalate can be used in studies of developmental toxicity and male reproductive toxicity .
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2
2 Cited Publications
Cat. No.: HY-I0508
CAS No.: 88-99-3
Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells .
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1
1 Cited Publications
Cat. No.: HY-W018392S
CAS No.: 1276197-22-8
Synonyms: MEHP-d4; Phthalic acid mono-2-ethylhexyl ester-d4
Mono-(2-ethylhexyl) phthalate-d4 is a deuterium labeled Mono-(2-ethylhexyl) phthalate (HY-W018392). Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD) .
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1
1 Cited Publications
Cat. No.: HY-N7143S
CAS No.: 478954-81-3
Monobutyl phthalate-d4 is the deuterium labeled Monobutyl phthalate . Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant .
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Cat. No.: HY-133668
CAS No.: 2306-33-4
Purity:  96.78%
Monoethyl phthalate is an orally active PDX-1 activator and the major hydrolytic metabolite of Diethyl phthalate (HY-Y0284) in vivo, with reproductive toxicity. Monoethyl phthalate targets aromatase (aromatase/CYP19A1) and PPAR to induce cell proliferation. The plasma protein binding rate of Monoethyl phthalate in rats and humans is lower than that of Diethyl phthalate. It exhibits significant enterohepatic circulation in rats and mainly accumulates in liver tissues. Monoethyl phthalate shows no estrogenic activity in estrogen-dependent human breast cancer cells. Monoethyl phthalate can be used in studies of reproductive toxicity and related environmental endocrine disruption mechanisms .
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Cat. No.: HY-B1945S
CAS No.: 93951-87-2
Synonyms: Bis(2-ethylhexyl) phthalate-d4; Ergoplast FDO-d4; ESBO-D 82-d4
DEHP-d4 is the deuterium labeled DEHP. DEHP (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite.
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Cat. No.: HY-W011848
CAS No.: 2528-16-7
Synonyms: 2-((Benzyloxy)carbonyl)benzoic acid
Monobenzyl phthalate is a phthalate metabolite (aromatic alkyl chain monophthalate) with oral activity, which acts as a male reproductive development inhibitor and antiandrogen in rat fetuses .
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Cat. No.: HY-133675
CAS No.: 40809-41-4
Purity:  97.44%
Synonyms: MECPP
Target:  

Drug Metabolite

Research Areas:  

Others

Mono (5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of di-(2-ethylhexyl) phthalate (DEHP). Di (2-ethylhexyl) phthalate is the primary plasticizer added to rigid polyvinyl chloride (PVC), and it imparts flexibility, temperature resistance, optical transparency, strength, and kink resistance .
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Cat. No.: HY-113220
CAS No.: 30833-53-5
Purity:  96.74%
Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium.
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Cat. No.: HY-Y1097
CAS No.: 4376-18-5
Synonyms: 2-(Methoxycarbonyl)benzoic acid
Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats .
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Cat. No.: HY-113220S
CAS No.: 1219802-26-2
Purity:  99.03%
Monoisobutyl phthalic acid-d4 is the deuterium labeled Monoisobutyl phthalic acid . Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium .
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Cat. No.: HY-Y1097S
CAS No.: 1276197-40-0
Synonyms: 2-(Methoxycarbonyl)benzoic acid-d4
Monomethyl phthalate-d4 (2-(Methoxycarbonyl)benzoic acid-d4) is the deuterium labeled Monomethyl phthalate. Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule .
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Cat. No.: HY-W587772
CAS No.: 1684398-38-6
Synonyms: MEHHTP
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Mono (2-ethyl-5-hydroxyhexyl) terephthalate (MEHHTP), a hydroxyl metabolite of the phthalate alternative Di-2-ethylhexyl terephthalate (DEHTP), is a liver X receptor α (LXRα) agonist with a binding energy of -7.41 kcal/mol. Mono (2-ethyl-5-hydroxyhexyl) terephthalate upregulates LXRα downstream targets such as SREBP-1c and FASN and increases lipogenic enzyme activity in hepatocytes, and elevating triglyceride (TG) levels. Mono (2-ethyl-5-hydroxyhexyl) terephthalate is promising for research of nonalcoholic fatty liver disease (NAFLD) .
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Cat. No.: HY-W011848S
CAS No.: 478954-83-5
Synonyms: 2-((Benzyloxy)carbonyl)benzoic acid-d4
Monobenzyl phthalate-d4 is the deuterium labeled Monobenzyl phthalate. Monobenzyl phthalate (2-((Benzyloxy)carbonyl)benzoic acid) is the urinary metabolite exposuring to phthalates, such as, diethylhexyl phthalate (DEHP) .
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Cat. No.: HY-133673S
CAS No.: 1346600-69-8
Synonyms: MCPP-d4
Mono(3-carboxypropyl) phthalate-d4 (MCPP-d4) is a deuterium labeled Mono(3-carboxypropyl) phthalate (HY-133673). Mono(3-carboxypropyl) phthalate (MCPP) is a metabolite of Di-n-octyl phthalate. Di-n-octyl phthalate (DnOP) is a plasticizer used in polyvinyl chloride plastics, cellulose esters, and polystyrene resins .
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Cat. No.: HY-W018392R
CAS No.: 4376-20-9
Synonyms: MEHP (Standard); Phthalic acid mono-2-ethylhexyl ester (Standard)
Mono-(2-ethylhexyl) phthalate (Standard) is the analytical standard of Mono-(2-ethylhexyl) phthalate. This product is intended for research and analytical applications. Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD) .
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Cat. No.: HY-I0508S
CAS No.: 87976-26-9
Phthalic acid-d4 is the deuterium labeled Phthalic acid. Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells .
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Cat. No.: HY-N7143R
CAS No.: 131-70-4
Monobutyl phthalate (Standard) is the analytical standard of Monobutyl phthalate. This product is intended for research and analytical applications. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant .
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Cat. No.: HY-W011848R
CAS No.: 2528-16-7
Synonyms: 2-((Benzyloxy)carbonyl)benzoic acid (Standard)
Monobenzyl phthalate (Standard) is the analytical standard of Monobenzyl phthalate. This product is intended for research and analytical applications. Monobenzyl phthalate (2-((Benzyloxy)carbonyl)benzoic acid) is the urinary metabolite exposuring to phthalates, such as, diethylhexyl phthalate (DEHP) .
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