4376-18-5
Chemical Structure
Monomethyl phthalate
Synonym(s): 2-(Methoxycarbonyl)benzoic acid
- CAS No.: 4376-18-5
- Formula:C9H8O4
- Molecular Weight:180.16
IUPAC Name: 2-(methoxycarbonyl)benzoic acid
InChIKey: FNJSWIPFHMKRAT-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1C(O)=O)OC
Biological Activity: Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats[1][2][3].
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Monomethyl phthalate | 99.41% | Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats. | ||||||||||||||||||||
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Monomethyl phthalate (Standard) | ≥98% | Monomethyl phthalate (Standard) is the analytical standard of Monomethyl phthalate. This product is intended for research and analytical applications. Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats. | ||||||||||||||||||||
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Monomethyl phthalate-d4 | Monomethyl phthalate-d4 (2-(Methoxycarbonyl)benzoic acid-d4) is the deuterium labeled Monomethyl phthalate. Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule. | |||||||||||||||||||||
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- [1]. Chong Liu, et al. Urinary biomarkers of phthalates exposure and risks of thyroid cancer and benign nodule. J Hazard Mater. 2020 Feb 5;383:121189. [Content Brief]
- [2]. Mathieu-Denoncourt J, et al. Chronic exposures to monomethyl phthalate in Western clawed frogs. Gen Comp Endocrinol. 2015 Aug 1;219:53-63. [Content Brief]
- [3]. Zhang X, et al. Metabolite Monomethyl Phthalate (MMP) Induces Oxidative Damage in Rat Erythrocytes: Role of Vitamins C and E. Toxics. 2025 May 7;13(5):379. [Content Brief]