478954-81-3
478954-81-3
Chemical Structure
Monobutyl phthalate-d4
- CAS No.: 478954-81-3
- Formula:C12H10D4O4
- Molecular Weight:226.26
IUPAC Name: 2-(butoxycarbonyl)benzoic-3,4,5,6-d4 acid
InChIKey: YZBOVSFWWNVKRJ-UGWFXTGHSA-N
SMILES: CCCCOC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(O)=O)=O
Biological Activity: Monobutyl phthalate-d4 is the deuterium labeled Monobutyl phthalate[1]. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant[2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Monobutyl phthalate-d4 | 98.43% | Monobutyl phthalate-d4 is the deuterium labeled Monobutyl phthalate. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant. | ||||||||||||||||||||
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Monobutyl phthalate (Standard) | 99.86% | Monobutyl phthalate (Standard) is the analytical standard of Monobutyl phthalate. This product is intended for research and analytical applications. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant. | ||||||||||||||||||||
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Monobutyl phthalate | 99.72% | Monobutyl phthalate is an orally active metabolite of Di-n-butyl phthalate (HY-Y0304) and an embryotoxic agent. Monobutyl phthalate regulates mesodermal lineage gene expression, inhibits uterine decidualization, reduces fetal testosterone levels without directly binding to the androgen receptor, and induces teratogenic effects during organogenesis. Monobutyl phthalate induces testicular oxidative stress and sperm abnormalities. Monobutyl phthalate can be used in studies of developmental toxicity and male reproductive toxicity. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. van Dartel DA, et al. Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate. Reprod Toxicol. 2009 Apr;27(2):93-102. [Content Brief]
- [3]. Ema M, et al. Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats. Congenit Anom (Kyoto). 2002 Dec;42(4):297-308. [Content Brief]
