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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
procarcinogens
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "procarcinogens" in MCE Product Catalog:
17
Target:
Research Areas:
Azoxymethane (AOM) is a colon carcinogen which leads to the formation of DNA adducts. Azomethane is a procarcinogen that requires metabolic activation via cytochrome P450 (P450) enzymes (primarily CYP2E1) .
Cat. No.: HY-E72102
Target:
Research Areas:
Human CYP3A4, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 3A4, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP3A4 is a human cytochrome P450 subtype belonging to the CYP3 family, as well as a major metabolic enzyme. It is predominantly expressed in human liver and intestine, metabolizes a variety of active compounds, and activates multiple procarcinogens .
Cat. No.: HY-E72103
Target:
Research Areas:
Human CYP1A1, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 1A1, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP1A1 is a human cytochrome P450 subtype belonging to the CYP1 family, as well as a major metabolic enzyme. Its expression is concentrated in tissues such as lung, breast, placenta and endometrium, and it can metabolize polycyclic aromatic hydrocarbons and estrogens into carcinogenic intermediates with DNA-damaging activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
