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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
rat erythrocytes
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "rat erythrocytes" in MCE Product Catalog:
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8 Publications Verification
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Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 μM). Entacapone can be used for the research of Parkinson's disease . Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
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1 Cited Publications
Cat. No.: HY-P1856
CAS No.: 33017-11-7
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
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1 Cited Publications
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AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats. AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively .
Cat. No.: HY-NP070
Synonyms: LTL
Cat. No.: HY-45509
CAS No.: 1208070-53-4
Synonyms: RAD150
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TLB 150 Benzoate (RAD150) is a nonsteroidal androgen receptor modulator with an IC50 value of 0.13 μM. TLB 150 Benzoate spontaneously cyclizes under physiological conditions to form RAD 179, resulting in a persistent, reversible, and slow neuronal conduction blockade. TLB 150 Benzoate can be used for research on neurological diseases .
Cat. No.: HY-W039898
CAS No.: 4163-65-9
Synonyms: 1,2,3,4,6-Penta-O-acetyl-α-D-mannopyranose
Cat. No.: HY-14280R
CAS No.: 130929-57-6
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Entacapone (Standard) is the analytical standard of Entacapone. This product is intended for research and analytical applications. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone can be used for the research of Parkinson's disease . Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
Cat. No.: HY-NP0186
Synonyms: RCA I (Biotinylated)
Cat. No.: HY-W763546A
CAS No.: 26403-72-5
Cat. No.: HY-P991792
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Cat. No.: HY-14280A
CAS No.: 1047659-02-8
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Entacapone sodium salt is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone sodium salt inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone sodium salt is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone sodium salt can be used for the research of Parkinson's disease . Entacapone sodium salt serves as as a inhibit of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
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(±)-Tocol is a synthetic vitamin E derivative.nlike (±)-α-tocopherol, (±)-tocol does not suppress retinol-induced erythrocyte hemolysis or increase microviscosity of rat liver phosphatidylcholine (PC) liposomes.
Cat. No.: HY-W237019
CAS No.: 55836-69-6
3-Ethoxybenzamide is an alkoxybenzamide compound with antibacterial activity and a FtsZ inhibitor that can cross the blood-brain barrier. 3-Ethoxybenzamide distributes widely and rapidly in vivo, rapidly reaches equilibrium between various tissues and blood, and is linearly taken up by hepatocytes. 3-Ethoxybenzamide is completely dependent on hepatic microsomal oxidation for clearance, with salicylamide as its major metabolite. 3-Ethoxybenzamide can be used for the study of bacterial infections .
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8-Phenyltheophylline is an adenosine receptor (adenosine receptor) antagonist. 8-Phenyltheophylline blocks adenosine-stimulated cAMP accumulation, inhibits tissue-selective cAMP hydrolysis, and antagonizes the inhibitory effects of adenosine. 8-Phenyltheophylline enhances apomorphine-induced rotational behavior in lesioned rats, reverses the analgesic effect of morphine in the rat hot plate test, and slightly enhances contractile responses of the atrium and ileum. 8-Phenyltheophylline can be used in studies related to unilateral nigrostriatal pathway injury .
Cat. No.: HY-184585
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UT-B-IN-2 is an orally active UT-B inhibitor, with an IC50 of 0.11 μM in mice and 0.054 μM in rats. UT-B-IN-2 induces diuretic effects in rats. UT-B-IN-2 can be used in the research of cardiovascular diseases and edema-related diseases .
Cat. No.: HY-103321
CAS No.: 145757-50-2
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N-Acetyl-L-leucyl-L-leucyl-L-methional is a Calpain II inhibitor with an IC50 of 0.24 μM against porcine Calpain II. N-Acetyl-L-leucyl-L-leucyl-L-methional forms a stable tetrahedral adduct with the thiol group at the active site of Calpain II, thereby inhibiting proteolytic activity. N-Acetyl-L-leucyl-L-leucyl-L-methionally inhibits cathepsins in a non-selective manner. N-Acetyl-L-leucyl-L-leucyl-L-methional reduces SARS-CoV-2 infection levels in human coronary artery endothelial cells in vitro. N-Acetyl-L-leucyl-L-leucyl-L-methional can be used in research related to cataracts and coronavirus infections .
Cat. No.: HY-189347
CAS No.: 3096111-98-4
CHNQD-01748 is an Antibacterial agent. CHNQD-01748 disrupts mature biofilms and bacterial membranes, leading to bacterial lysis. CHNQD-01748 exhibits selective antibacterial activity against S. aureus and MRSA, with negligible activity against other Gram-positive bacteria, Gram-negative bacteria, and fungi. CHNQD-01748 can be used for research on MRSA infections .
Cat. No.: HY-187757
CAS No.: 77749-81-6
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RX-RA 85 is an orally active phosphodiesterase modulator that exerts antiplatelet and antitumor effects by elevating intracellular cAMP levels, inhibiting platelet and tumor cell PDE activity, and modulating cytoskeletal organization. RX-RA 85 can be used in studies of rat breast cancer and metastatic tumors .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
