1 Result for "

rat hypothalamic synaptosomes

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "rat hypothalamic synaptosomes" in MCE Product Catalog:

Cat. No.: HY-110023
CAS No.: 60525-15-7
Purity:  98.27%
Target:  

Serotonin Transporter

Research Areas:  

Neurological Disease

Zimelidine dihydrochloride is an orally active selective serotonin reuptake inhibitor. Zimelidine dihydrochloride competitively inhibits central 5-HT uptake and desensitizes 5-HT autoreceptors in dorsal raphe nucleus. Zimelidine dihydrochloride time-dependently modulates 5-HT neuronal firing and hippocampal CA3 responses. Zimelidine dihydrochloride strengthens central serotonergic neurotransmission and produces related behavioral changes. Zimelidine dihydrochloride exerts anxiolytic, analgesic, feeding-suppressive and tolerance-attenuating effects. Zimelidine dihydrochloride is used for the study of depressive disorders and analgesic tolerance .
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