Search Result

Results for "

thymic stromal lymphopoietin (TSLP)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CCR (1) Interleukin Related (8) Leukotriene Receptor (1) STAT (2)
By Research Areas:	Cancer (2) Inflammation/Immunology (11) Metabolic Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990774

Verekitug ASP-7266; TRAB-1; UPB-101	Interleukin Related	Inflammation/Immunology
Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting *TSLP*-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .

HY-P991162

Tilrekimig PF-07275315	Interleukin Related	Inflammation/Immunology
Tilrekimig (PF-07275315) is a monoclonal antibody targeting human interleukin-4 (IL-4), interleukin-13 (IL-13) and thymic stromal lymphopoietin (TSLP). Tilrekimig can be used in the research of allergic and inflammatory diseases, such as asthma and atopic dermatitis .

HY-P990933

Ocankitug CM-326	Interleukin Related	Inflammation/Immunology
Ocankitug (CM-326) is a humanized IgG1κ antibody targeting thymic stromal lymphopoietin (TSLP). It can be used for research on type 2 inflammatory respiratory diseases, including moderate to severe asthma, chronic sinusitis with nasal polyps, etc.

HY-P990023

Bempikibart ADX-914	Interleukin Related	Metabolic Disease Inflammation/Immunology
Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .

HY-P99872

Ecleralimab CSJ-117; NVP-CSJ117	Interleukin Related	Inflammation/Immunology
Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin (TSLP). Ecleralimab significantly attenuates allergen-induced airway responses and inflammation. Ecleralimab can be used for the study of inhaled asthma .

HY-P991424

GSK2618960	Interleukin Related STAT	Inflammation/Immunology
GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used for the research of autoimmune and allergic inflammatory diseases. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P991717

Sunakiment AZD-8630	Interleukin Related	Inflammation/Immunology Cancer
Sunakiment is a humanized IgG1λ monoclonal antibody inhibitor targeting **Thymic stromal lymphopoietin (TSLP)**. Sunakiment can be used for inflammatory and immune system disorders like ulcerative colitis, rheumatoid arthritis and allergy and cancers research .

HY-W341962

Halometasone	Leukotriene Receptor	Inflammation/Immunology
Halometasone is a corticosteroid compound that can reduce the expression of serum leukotriene B4 (LTB4) and thymic stromal lymphopoietin (TSLP). Halometasone can be used in research on psoriasis and eczematous skin diseases .

HY-207120

TSLP-IN-1	Interleukin Related	Inflammation/Immunology
TSLP-IN-1 is a potent thymic stromal lymphopoietin (TSLP) inhibitor. TSLP-IN-1 disrupts *TSLP-TSLPR* protein-protein interaction, and downregulates IL-4 and IL-13. TSLP-IN-1 can be used for the research of inflammation diseases, such as skin disease, asthma, and allergies .

HY-P992378

HZ-1127	CCR STAT	Inflammation/Immunology Cancer
HZ-1127 is a **thymic stromal lymphopoietin (TSLP) inhibitor. HZ-1127 selectively binds to TSLP, blocks receptor complex interaction, inhibits STAT5** activation, downstream inflammatory signaling, and TSLP-induced CCL17 and CCL22 secretion. HZ-1127 can be used for the research of allergic diseases and cancer .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990774

Verekitug ASP-7266; TRAB-1; UPB-101	Interleukin Related	Inflammation/Immunology
Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting *TSLP*-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .

HY-P991162

Tilrekimig PF-07275315	Interleukin Related	Inflammation/Immunology
Tilrekimig (PF-07275315) is a monoclonal antibody targeting human interleukin-4 (IL-4), interleukin-13 (IL-13) and thymic stromal lymphopoietin (TSLP). Tilrekimig can be used in the research of allergic and inflammatory diseases, such as asthma and atopic dermatitis .

HY-P990933

Ocankitug CM-326	Interleukin Related	Inflammation/Immunology
Ocankitug (CM-326) is a humanized IgG1κ antibody targeting thymic stromal lymphopoietin (TSLP). It can be used for research on type 2 inflammatory respiratory diseases, including moderate to severe asthma, chronic sinusitis with nasal polyps, etc.

HY-P990023

Bempikibart ADX-914	Interleukin Related	Metabolic Disease Inflammation/Immunology
Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .

HY-P99872

Ecleralimab CSJ-117; NVP-CSJ117	Interleukin Related	Inflammation/Immunology
Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin (TSLP). Ecleralimab significantly attenuates allergen-induced airway responses and inflammation. Ecleralimab can be used for the study of inhaled asthma .

HY-P991424

GSK2618960	Interleukin Related STAT	Inflammation/Immunology
GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used for the research of autoimmune and allergic inflammatory diseases. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P991717

Sunakiment AZD-8630	Interleukin Related	Inflammation/Immunology Cancer
Sunakiment is a humanized IgG1λ monoclonal antibody inhibitor targeting **Thymic stromal lymphopoietin (TSLP)**. Sunakiment can be used for inflammatory and immune system disorders like ulcerative colitis, rheumatoid arthritis and allergy and cancers research .

HY-P992378

HZ-1127	CCR STAT	Inflammation/Immunology Cancer
HZ-1127 is a **thymic stromal lymphopoietin (TSLP) inhibitor. HZ-1127 selectively binds to TSLP, blocks receptor complex interaction, inhibits STAT5** activation, downstream inflammatory signaling, and TSLP-induced CCL17 and CCL22 secretion. HZ-1127 can be used for the research of allergic diseases and cancer .

HY-P992452

RO-5469754	Inhibitory Antibodies	Inflammation/Immunology
RO-5469754 is a humanized monoclonal antibody that specifically binds to human **thymic stromal lymphopoietin** (TSLP). RO-5469754 blocks the binding of hTSLP to its receptor complex, thereby neutralizing TSLP-mediated biological activities, and does not cross-react with TSLP from cynomolgus monkeys or mice. RO-5469754 can be further used to generate the bispecific antibody TAVO101 × IL4R-dupi .

Species:	Human (10) Rat (1) Mouse (5) Cynomolgus (5)
Tag:	His (16) Avi (6) Myc (1) Fc (5)
Source:	HEK293 (20) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704947

	TSLP Protein, Human (HEK293, Fc) thymic stromal lymphopoietin; thymic stromal lymphopoietin protein TSLP; Tslp; TSLP protein; TSLP_HUMAN	Human	HEK293

HY-P70703

	TSLP Protein, Cynomolgus (His) thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin; TSLP	Cynomolgus	E. coli
	Thymic stromal lymphopoietin (TSLP) is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. TSLP mainly impacts myeloid cells and promotes T helper type 2 (TH2) cell responses associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. TSLP Protein, Cynomolgus (His) is the recombinant cynomolgus-derived TSLP protein, expressed by E. coli , with C-6*His labeled tag and Q37E mutation.

HY-P700601

	TSLP Protein, Human (HEK293, His-Myc) thymic stromal lymphopoietin; thymic stromal lymphopoietin protein TSLP; Tslp; TSLP protein; TSLP_HUMAN	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (HEK293, His-Myc) is the recombinant human-derived TSLP protein, expressed by HEK293 , with N-Myc, N-6*His labeled tag.

HY-P70626

	TSLP Protein, Mouse (HEK293, Fc) thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin; Tslp	Mouse	HEK293
	TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TSLP protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704949

	TSLP Protein, Mouse (HEK293, His) thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin; Tslp	Mouse	HEK293

HY-P704948

	TSLP Protein, Human (R127A, R130A, HEK293, Fc) thymic stromal lymphopoietin; thymic stromal lymphopoietin protein TSLP; Tslp; TSLP protein; TSLP_HUMAN	Human	HEK293

HY-P78789

	TSLP Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin; TSLP	Cynomolgus	HEK293
	TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is the recombinant cynomolgus-derived TSLP protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of TSLP Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is 131 a.a., with molecular weight of ~12 kDa.

HY-P78790

	TSLP Protein, Mouse (Biotinylated, HEK293, His-Avi) thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin; TSLP	Mouse	HEK293
	TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived TSLP protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of TSLP Protein, Mouse (Biotinylated, HEK293, His-Avi) is 121 a.a., with molecular weight of 25-33 kDa.

HY-P70818

	TSLP Protein, Human (HEK293, His) thymic stromal lymphopoietin; TSLP	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (HEK293, His) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P78046

	TSLP Protein, Cynomolgus (HEK293, His) thymic stromal lymphopoietin; TSLP	Cynomolgus	HEK293
	TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TSLP protein, expressed by HEK293 , with C-8*His labeled tag.

HY-P78613

	TSLP Protein, Rat (HEK293, His) thymic stromal lymphopoietin; TSLP	Rat	HEK293
	TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Rat (HEK293, His) is the recombinant rat-derived TSLP protein, expressed by HEK293 , with C-His labeled tag. The total length of TSLP Protein, Rat (HEK293, His) is 118 a.a., with molecular weight of 20-30 kDa.

HY-P78532

	TSLP Protein, Human (HEK293, His-Avi) thymic stromal lymphopoietin; TSLP	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (HEK293, His-Avi) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78047

	TSLP Protein, Cynomolgus (Biotinylated, HEK293, His) thymic stromal lymphopoietin; TSLP	Cynomolgus	HEK293
	TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived TSLP protein, expressed by HEK293 , with C-His labeled tag.

HY-P78224

	TSLP Protein, Human (Biotinylated, HEK293, His-Avi) thymic stromal lymphopoietin; TSLP	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78658

	TSLP Protein, Human (R127A, R130A, HEK293, His) thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin; TSLP	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (R127A, R130A, HEK293, His) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-His labeled tag and R127A, R130A, , , mutation.

HY-P78659

	TSLP Protein, Human (R127A, R130A, HEK293, mFc) thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin; TSLP	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (R127A, R130A, HEK293, mFc) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-mFc labeled tag and R127A, R130A mutation.

HY-P78565

	TSLP Protein, Cynomolgus (R127A, R130S, HEK293, His) thymic stromal lymphopoietin; TSLP	Cynomolgus	HEK293
	TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Cynomolgus (R127A, R130S, HEK293, His) is the recombinant cynomolgus-derived TSLP protein, expressed by HEK293 , with C-His labeled tag.

HY-P78533

	TSLP Protein, Human (R127A, R130A, HEK293, His-Avi) thymic stromal lymphopoietin; TSLP	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (R127A, R130A, HEK293, His-Avi) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-Avi, C-His labeled tag and R127A, R130A mutation.

HY-P78225

	TSLP Protein, Human (Biotinylated, R127A, R130A, HEK293, His-Avi) thymic stromal lymphopoietin; TSLP	Human	HEK293
	TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (Biotinylated, R127A, R130A, HEK293, His-Avi) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-Avi, C-His labeled tag and R127A, R130A mutation.

HY-P70823

	TSLP R Protein, Mouse (HEK293, Fc) CRL2; CRLF2; CRL2 cytokine receptor; cytokine receptor-like factor 2; ILXR; IL-XR; P2RY8/CRLF2 fusion; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin receptor; TSLP receptor; TSLPR	Mouse	HEK293
	Cytokine receptor-like factor 2 (Crlf2), also known as thymic stromal lymphopoietin (TSLP) receptor, is a receptor for TSLP. Crlf2 can forms a functional complex with TSLP and IL7RA, and overexpression of Crlf2 stimulates cell proliferation through activation of the JAK-STAT pathway. The expression of Crlf2 usually upregulates and mutated in populations of B-progenitor acute lymphoblastic leukemia (B-ALL). TSLP R Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TSLP R protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70989

	TSLP R Protein, Mouse (HEK293, His) CRL2; CRLF2; CRL2 cytokine receptor; Cytokine receptor-like 2; cytokine receptor-like factor 2; ILXR; IL-XR; P2RY8/CRLF2 fusion; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin receptor; TSLP receptor; TSLPR	Mouse	HEK293
	Cytokine receptor-like factor 2 (Crlf2), also known as thymic stromal lymphopoietin (TSLP) receptor, is a receptor for TSLP. Crlf2 can forms a functional complex with TSLP and IL7RA, and overexpression of Crlf2 stimulates cell proliferation through activation of the JAK-STAT pathway. The expression of Crlf2 usually upregulates and mutated in populations of B-progenitor acute lymphoblastic leukemia (B-ALL). TSLP R Protein, Mouse (HEK293, His) is the recombinant mouse-derived TSLP R protein, expressed by HEK293 , with C-6*His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: