38 Results for "

thymic stromal lymphopoietin (TSLP)

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "thymic stromal lymphopoietin (TSLP)" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P7057
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P70626
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-P991162
CAS No.: 2981469-90-1
Synonyms: PF-07275315
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Tilrekimig (PF-07275315) is a monoclonal antibody targeting human interleukin-4 (IL-4), interleukin-13 (IL-13) and thymic stromal lymphopoietin (TSLP). Tilrekimig can be used in the research of allergic and inflammatory diseases, such as asthma and atopic dermatitis .
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Cat. No.: HY-P990933
CAS No.: 2803351-66-6
Synonyms: CM-326

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ocankitug (CM-326) is a humanized IgG1κ antibody targeting thymic stromal lymphopoietin (TSLP). It can be used for research on type 2 inflammatory respiratory diseases, including moderate to severe asthma, chronic sinusitis with nasal polyps, etc.
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Cat. No.: HY-P990023
CAS No.: 2622254-57-1
Synonyms: ADX-914

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .
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Cat. No.: HY-P99872
CAS No.: 2415207-91-7
Synonyms: CSJ-117; NVP-CSJ117

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin (TSLP). Ecleralimab significantly attenuates allergen-induced airway responses and inflammation. Ecleralimab can be used for the study of inhaled asthma .
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Cat. No.: HY-P991424

Research Areas:  

Inflammation/Immunology

GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used for the research of autoimmune and allergic inflammatory diseases. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991717
CAS No.: 2928519-36-0
Synonyms: AZD-8630
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Sunakiment (AZD-8630) is a humanized IgG1λ monoclonal antibody inhibitor targeting thymic stromal lymphopoietin (TSLP), which enables direct airway delivery via a dry powder inhaler formulation. Sunakiment binds to TSLP and blocks its pro-inflammatory signal transduction. It is applicable to research on refractory asthma, asthma, and moderate-to-severe asthma .
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Cat. No.: HY-W341962
CAS No.: 50629-82-8
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

Halometasone is a corticosteroid compound that can reduce the expression of serum leukotriene B4 (LTB4) and thymic stromal lymphopoietin (TSLP). Halometasone can be used in research on psoriasis and eczematous skin diseases .
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Cat. No.: HY-P811326
Synonyms: thymic stromal lymphopoietin, thymic stroma-derived lymphopoietin, Tslp

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P70703
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Cynomolgus
Source:  
E. coli
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Cat. No.: HY-P70818
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78046
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P78613
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P704947
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704949
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78532
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700601
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78047
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: thymic Stroma-Derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Species:  
Cynomolgus
Source:  
HEK293
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