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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
tnf alpha treatment
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "tnf alpha treatment" in MCE Product Catalog:
Cat. No.: HY-164919
CAS No.: 2847102-44-5
Synonyms: XMT-2056
Research Areas:
Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate (ADC) targeting HER2, linked to a payload composed of XMT-1519 conjugate-1 (HY-148067) and STING agonist-20 (HY-148068). Calotatug ginistinag activates the STING signaling pathway in tumor cells and tumor-resident immune cells, induces the production of type I interferons and cytokines (CXCL10, IFN-β, IL-6, TNF-α, triggers innate anti-tumor immune responses, and exerts a bystander effect. Calotatug ginistinag exhibits efficacy against HER2-expressing cancer cells in co-culture with PBMCs. Calotatug ginistinag induces tumor regression and reduces systemic inflammation in various tumor models. Combination treatment with Calotatug ginistinag, Trastuzumab (HY-P9907) and T-DXd (HY-138298) yields benefits. Calotatug ginistinag can be used in studies related to HER2-expressing solid tumors such as breast cancer, gastric cancer and ovarian cancer .
Cat. No.: HY-N0626A
CAS No.: 24634-61-5
Synonyms: Sorbic acid potassium
Cat. No.: HY-18862
CAS No.: 1056164-52-3
Target:
Research Areas:
PF-03715455 is a potent inhaled p38 MAPK inhibitor. PF-03715455 shows some selectivity for p38α over p38β with respective IC50 values of 0.88 and 23 nM. PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 has potential for the treatment of COPD (chronic obstructive pulmonary disease) .
Cat. No.: HY-N0626AR
CAS No.: 24634-61-5
Synonyms: Sorbic acid potassium (Standard)
Cat. No.: HY-P11107
CAS No.: 2375823-45-1
Target:
Research Areas:
Cat. No.: HY-N6927
CAS No.: 64657-21-2
Synonyms: Coleonol B
Category:
Labiatae Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology Pueraria montana (Lour.) Merr.
Target:
Cat. No.: HY-W001288
CAS No.: 1074-86-8
Cat. No.: HY-N11996
CAS No.: 59163-53-0
Category:
Liliaceae Aloe vera (L.) Burm. f. Phenols Polyphenols Plants
Target:
Cat. No.: HY-N6927R
CAS No.: 64657-21-2
Synonyms: Coleonol B (Standard)
Cat. No.: HY-P4096A
Target:
Research Areas:
Cat. No.: HY-W001288S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
