1074-86-8
Chemical Structure
Indole-4-carboxaldehyde
- CAS No.: 1074-86-8
- Formula:C9H7NO
- Molecular Weight:145.16
IUPAC Name: 1H-indole-4-carbaldehyde
InChIKey: JFDDFGLNZWNJTK-UHFFFAOYSA-N
SMILES: O=CC1=CC=CC2=C1C=CN2
Biological Activity: Indole-4-carboxaldehyde is an ergot alkaloid precursor that regulates glycosylation and inflammation. Indole-4-carboxaldehyde upregulates Glo-1, inhibits MGO-induced NF-κB activation, and suppresses MGO-induced expression of TNF-α and IFN-γ. Indole-4-carboxaldehyde inhibits MGO-induced formation of advanced glycation end products (AGE) and expression of their receptor (RAGE). Indole-4-carboxaldehyde is a core metabolite produced in the pedicels of Summer Black grapes after exogenous gibberellin treatment, and it directly promotes fruit enlargement and fruit set of Summer Black grapes. Indole-4-carboxaldehyde can be used in studies related to hepatic steatosis and plant growth regulation[1][2][3].
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Indole-4-carboxaldehyde | 99.32% | Indole-4-carboxaldehyde is an ergot alkaloid precursor that regulates glycosylation and inflammation. Indole-4-carboxaldehyde upregulates Glo-1, inhibits MGO-induced NF-κB activation, and suppresses MGO-induced expression of TNF-α and IFN-γ. Indole-4-carboxaldehyde inhibits MGO-induced formation of advanced glycation end products (AGE) and expression of their receptor (RAGE). Indole-4-carboxaldehyde is a core metabolite produced in the pedicels of Summer Black grapes after exogenous gibberellin treatment, and it directly promotes fruit enlargement and fruit set of Summer Black grapes. Indole-4-carboxaldehyde can be used in studies related to hepatic steatosis and plant growth regulation. | ||||||||||||||||||||
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Indole-4-carboxaldehyde-13C | Indole-4-carboxaldehyde-13C is the 13C-labeled Indole-4-carboxaldehyde (HY-W001288). Indole-4-carboxaldehyde is an ergot alkaloid precursor that regulates glycosylation and inflammation. Indole-4-carboxaldehyde upregulates Glo-1, inhibits MGO-induced NF-κB activation, and suppresses MGO-induced expression of TNF-α and IFN-γ. Indole-4-carboxaldehyde inhibits MGO-induced formation of advanced glycation end products (AGE) and expression of their receptor (RAGE). Indole-4-carboxaldehyde is a core metabolite produced in the pedicels of Summer Black grapes after exogenous gibberellin treatment, and it directly promotes fruit enlargement and fruit set of Summer Black grapes. Indole-4-carboxaldehyde can be used in studies related to hepatic steatosis and plant growth regulation. | |||||||||||||||||||||
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- [1]. Cha, S.-H., et al. Indole-4-carboxaldehyde Isolated from Seaweed, Sargassum thunbergii, Attenuates Methylglyoxal-Induced Hepatic Inflammation. Marine Drugs, 2019, 17(9): 486.
- [2]. Wu J, et al. Synthesis and Antiproliferative Activity of New Thiosemicarboxamide Derivatives. Chemistry & biodiversity. 2021 Dec;18(12):e2100671. [Content Brief]
- [3]. Zhang, K., et al. Effects of Exogenous GA on the Metabolism of Summer Black Grape Rachis. Journal of Shanxi Agricultural Sciences, 2024, 52(4): 108-117.
