Aloenin aglycone
Aloenin aglycone (compound 13) is an NF-κB inhibitor that can be isolated from aloe exudate. Aloenin aglycone inhibits TNFα-induced NF-κB transcriptional activity (IC50: 18.7 μM). Aloenin aglycone (10 μM) also reduced inducible nitric oxide synthase (iNOS) and intercellular adhesion molecule 1 (ICAM-1) gene expression after treatment of HepG2 cells with 10 ng/mL TNFα.
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- CAS No.: 59163-53-0
- 화학식: C13H12O5
- 분자량:248.23
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
intercellular adhesion molecule-1 (ICAM-1)[1]
Chemical Information
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CAS No. 59163-53-0
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분자량 248.23
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화학식 C13H12O5
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SMILES
O=C1OC(C2=C(C)C=C(O)C=C2O)=CC(OC)=C1
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)