Aloenin aglycone
Aloenin aglycone (compound 13) is an NF-κB inhibitor that can be isolated from aloe exudate. Aloenin aglycone inhibits TNFα-induced NF-κB transcriptional activity (IC50: 18.7 μM). Aloenin aglycone (10 μM) also reduced inducible nitric oxide synthase (iNOS) and intercellular adhesion molecule 1 (ICAM-1) gene expression after treatment of HepG2 cells with 10 ng/mL TNFα.
For research use only. We do not sell to patients.
- CAS No.: 59163-53-0
- Formula: C13H12O5
- Molecular Weight:248.23
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
intercellular adhesion molecule-1 (ICAM-1)[1]
Chemical Information
-
CAS No. 59163-53-0
-
Molecular Weight 248.23
-
Formula C13H12O5
-
SMILES
O=C1OC(C2=C(C)C=C(O)C=C2O)=CC(OC)=C1
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz