1. Search Result
Search Result
Results for "

trans isomer

" in MedChemExpress (MCE) Product Catalog:

60

Inhibitors & Agonists

3

Biochemical Assay Reagents

13

Natural
Products

3

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12495
    ISRIB (trans-isomer)
    Maximum Cited Publications
    46 Publications Verification

    PERK Autophagy Apoptosis Neurological Disease
    ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM).
    ISRIB (trans-isomer)
  • HY-N0351
    p-Coumaric acid
    3 Publications Verification

    trans-4-Hydroxycinnamic acid

    Endogenous Metabolite Bacterial Apoptosis Inflammation/Immunology Cancer
    p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .
    p-Coumaric acid
  • HY-N2341
    Palmitelaidic acid
    3 Publications Verification

    9-trans-Hexadecenoic acid; trans-Palmitoleic acid

    AMPK PPAR Glucokinase Metabolic Disease
    Palmitelaidic acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.
    Palmitelaidic acid
  • HY-125021
    2BAct
    3 Publications Verification

    Eukaryotic Initiation Factor (eIF) Neurological Disease
    2BAct is a highly selective, orally active, and CNS-penetrant eIF2B (eukaryotic initiation factor 2B) activator with an EC50 of 33 nM. 2BAct prevents neurological defects caused by a chronic integrated stress response. 2BAct displays improved solubility and pharmacokinetics relative to eIF2B activator ISRIB trans-isomer (HY-12495) .
    2BAct
  • HY-117215

    Environmental Pollutants Biochemical Assay Reagents Others
    Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.
    β-Ocimene
  • HY-107425A

    PROTACs Epigenetic Reader Domain Cancer
    cis-MZ 1 is a cis isomer of meso-zeaxanthin, a xanthophyll carotenoid component of total zeaxanthin measured in serum and egg yolks.cis-MZ 1 is a triphenyltin benzoate that adopts either a tetrahedral monomeric structure (I) or a trans-SnR3O2 polymeric structure (III), with structure determined by a balance of steric and electronic factors .
    cis-MZ 1
  • HY-N1867

    PPAR Metabolic Disease
    trans-Cinnamyl alcohol is a trans-isomer of Cinnamyl alcohol. Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity. trans-Cinnamyl alcohol, belongs to the class of organic compounds known as cinnamyl alcohols, is a primary metabolite .
    trans-Cinnamyl alcohol
  • HY-N0351R

    trans-4-Hydroxycinnamic acid (Standard)

    Reference Standards Endogenous Metabolite Bacterial Apoptosis Inflammation/Immunology Cancer
    p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid. This product is intended for research and analytical applications. p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .
    p-Coumaric acid (Standard)
  • HY-134819

    (+)-trans-ML-SI3

    TRP Channel Cancer
    (1S,2S)-ML-SI3 is a trans-isomer of ML-SI3 that targets all three isoforms of TRPML. (1S,2S)-ML-SI3 is an activator of TRPML2 and TRPML3 (EC50=2.7 μM/10.8 μM) and a potent inhibitor of TRPML1 (IC50=5.9 μM) .
    (1S,2S)-ML-SI3
  • HY-151385A

    STAT Interleukin Related IFNAR JAK Cancer
    (R,R)-VVD-118313 is the isomer of VVD-118313 (HY-151385). VVD-118313 is a selective JAK1 inhibitor and blocks JAK1-dependent trans-phosphorylation and cytokine signaling. VVD-118313 can be used for research of cancer . (R,R)-VVD-118313 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (R,R)-VVD-118313
  • HY-W073501

    trans-2-Pentenedioic acid

    Drug Isomer Endogenous Metabolite Cardiovascular Disease Metabolic Disease
    trans-Glutaconic acid (trans-2-Pentenedioic acid) is the trans isomer of Glutaconic acid (HY-W073501A). trans-Glutaconic acid is a neurotoxic metabolite. trans-Glutaconic acid induces weak neurotoxicity in cultured cerebral neocortical neurons. trans-Glutaconic acid elicits significant electrophysiological responses in rat neocortical wedge preparations at high concentrations. trans-Glutaconic acid can be used in studies related to glutaric acidemia type 1 .
    trans-Glutaconic acid
  • HY-151232

    (E/Z)-PRN1008

    Btk Inflammation/Immunology
    (E/Z)-Rilzabrutinib ((E/Z)-PRN1008) is a cis-trans isomer of Rilzabrutinib (HY-112166). Rilzabrutinib is a BTK inhibitor .
    (E/Z)-Rilzabrutinib
  • HY-123669A

    P2Y Receptor Cardiovascular Disease
    Trans-R-138727 is the trans isomer of R-138727 (HY-123669). R-138727 is the active metabolite of the antiplatelet agent Prasugrel (HY-15284). R-138727 is an irreversible inhibitor for the platelet receptor P2Y12, and inhibits ADP-induced platelet activation and aggregation .
    trans-R-138727
  • HY-135163

    (5E)-Latanoprost; 5,6-trans-Latanoprost

    Prostaglandin Receptor Others
    trans-Latanoprost (5,6-trans-Latanoprost) is the trans isomer of Latanoprost (HY-B0577). trans-Latanoprost is promising for research of glaucoma and high eye pressure .
    trans-Latanoprost
  • HY-124141

    trans-9-Tetradecenoic acid

    Endogenous Metabolite Metabolic Disease
    Myristelaidic acid (trans-9-Tetradecenoic acid), a 14-carbon trans fatty acid, is the trans isomer of Myristoleic acid. Myristelaidic acid is found in most animal fats .
    Myristelaidic acid
  • HY-76542A
    5,6-trans-Vitamin D2
    1 Publications Verification

    5,6-trans-Ergocalciferol; 5,6-trans-Calciferol; 5,6-trans-Ercalciol

    Others Others
    5,6-trans-Vitamin D2 is the isomer of Vitamin D2 .
    5,6-trans-Vitamin D2
  • HY-18706

    trans-MK-341; trans-SB 252218

    Angiotensin Receptor Drug Isomer Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    trans-Tranilast (trans-MK-341) is an isomer of Tranilast (HY-B0195), and an anti-allergy agent used in studies of bronchial asthma, allergic rhinitis, and atopic dermatitis .
    trans-Tranilast
  • HY-W075885

    trans-platinumdiamminedichloride

    DNA Alkylator/Crosslinker Others
    trans-Platinum(II)diammine dichloride (trans-platinumdiamminedichloride) is a geometric isomer of Cisplatin (HY-17394). Trans-Platinum(II)diammine dichloride is a DNA cross-linking agent that induces significant DNA cross-link damage while exhibiting low cytotoxicity. Trans-Platinum(II)diammine dichloride is useful for studying DNA-protein cross-links .
    trans-Platinum(II)diammine dichloride
  • HY-75992

    VD/VDR Others
    trans-Doxercalciferol is an isomer of Doxercalciferol. Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease .
    trans-Doxercalciferol
  • HY-119254A

    Epigenetic Reader Domain Metabolic Disease
    trans-BAY-850 is the trans isomer of BAY-850 (HY-119254). BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM.
    trans-BAY-850
  • HY-113326

    trans-Phytoene

    Reactive Oxygen Species (ROS) Cancer
    Phytoene (trans-Phytoene) is a carotene pigment. Phytoene is the precursor of all carotenoids. Phytoene is the predominant PT isomer in most carotenogenic organisms. Phytoene can delay the skin tumors appearance and reduce their number in mice that are induced the tumors with UV-B light. Phytoene leads to protection against oxidative stress and malignant transformation. Phytoene inhibits the proliferation of breast cancer cells .
    Phytoene
  • HY-W342979

    trans-Petroselinic acid; trans-6-Octadecenoic acid

    Drug Isomer Others
    Petroselaidic acid is a trans fatty acid and the trans isomer of Petroselinic acid (HY-113362). Petroselaidic acid can be found in dairy products such as cow's milk and goat's milk .
    Petroselaidic acid
  • HY-B0191A

    5,6-trans-AGN 192024

    Prostaglandin Receptor Endocrinology Cancer
    5,6-trans-Bimatoprost is the isomer of Bimatoprost (HY-B0191), and can be used as an experimental control. Bimatoprost is a prostaglandin analogue that can be used in studies of ocular hypertension and glaucoma and also has anti-fat formation effects.
    5,6-trans-Bimatoprost
  • HY-145670

    Akt MDM-2/p53 Cancer
    cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase .
    cis,trans-Germacrone
  • HY-116459

    AF102A hydrochloride

    mAChR Neurological Disease
    Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease .
    trans-Cevimeline hydrochloride
  • HY-N2341S

    AMPK PPAR Glucokinase Metabolic Disease
    Palmitelaidic acid-d13 is the deuterium labeled Palmitelaidic Acid. Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.
    Palmitelaidic acid-d13
  • HY-N8356A

    9-cis-Retinyl palmitate

    Endogenous Metabolite Others
    9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer formed by vitamin A palmitate in corn flakes. 9-cis-Vitamin A palmitate has a biological activity of 26% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A .
    9-cis-Vitamin A palmitate
  • HY-W700726

    Isotope-Labeled Compounds Others
    cis-Atovaquone-d5 (contains 10% trans isomer) is the deuterium labeled cis-Atovaquone.
    cis-Atovaquone-d5 (contains 10% trans isomer)
  • HY-W753927

    C18:2(9E,12Z); C18:2 n-6

    Endogenous Metabolite Metabolic Disease
    9(E),12(Z)-Octadecadienoic acid is an ω-6 polyunsaturated fatty acid and an isomer of linoleic acid (HY-N0729) that contains a trans double bond at the C9 position. It has been found as a minor component of bovine milk fat and in partially hydrogenated vegetable oils. 9(E),12(Z)-Octadecadienoic acid levels increase in rabbit meat following supplementation with heated sunflower oil, α-tocopheryl acetate, and zinc.
    9(Z)​,​12(E)​-​Octadecadienoic Acid
  • HY-166088

    trans-9-Tetradecenoic acid sodium

    Endogenous Metabolite Metabolic Disease
    Myristelaidic acid (trans-9-Tetradecenoic acid) sodium, a 14-carbon trans fatty acid, is the trans isomer of Myristoleic acid. Myristelaidic acid is found in most animal fats .
    Myristelaidic acid sodium
  • HY-114850

    5-trans-PGF2β

    Prostaglandin Receptor Endocrinology
    5-trans Prostaglandin F2β (5-trans-PGF2β) is the 9β-hydroxy isomer of 5-trans PGF2α .
    5-trans Prostaglandin F2β
  • HY-113756

    Prostaglandin Receptor Others
    trans-Latanoprost acid is an isomer of Latanoprost acid. trans-Latanoprost acid may have the activity of reducing intraocular pressure. trans-Latanoprost acid is mainly prepared as an analytical standard for impurity detection and quantification .
    trans-​Latanoprost acid
  • HY-122178

    PGE synthase Cardiovascular Disease
    5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069 (HY-121825). 5-trans U-44069 inhibits prostaglandin E2 synthase activity .
    5-trans U-44069
  • HY-134211

    Endogenous Metabolite Others
    Z-2-Octenoic acid is the Z-isomer of 2-Octenoic acid. trans-2-Octenoic acid is a metabolite of Mucor species.
    (Z)-2-Octenoic acid
  • HY-161414

    CXCR Others
    trans-VUF25471 (Compound trans-3e) is a photoswitchable ACKR3 agonist. trans-VUF25471 binds and activates ACKR3 at 10-fold lower concentrations compared to its cis-isomer .
    trans-VUF25471
  • HY-113465A

    Endogenous Metabolite Inflammation/Immunology
    11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4). Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum .
    11-trans Leukotriene E4
  • HY-N1867R

    Reference Standards PPAR Metabolic Disease
    trans-Cinnamyl alcohol is a trans-isomer of Cinnamyl alcohol. Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity. trans-Cinnamyl alcohol, belongs to the class of organic compounds known as cinnamyl alcohols, is a primary metabolite .
    trans-Cinnamyl alcohol (Standard)
  • HY-76542AR

    5,6-trans-Ergocalciferol (Standard); 5,6-trans-Calciferol (Standard); 5,6-trans-Ercalciol (Standard)

    Drug Isomer VD/VDR Reference Standards Others
    5,6-trans-Vitamin D2 (Standard) is the analytical standard of 5,6-trans-Vitamin D2. This product is intended for research and analytical applications. 5,6-trans-Vitamin D2 is the isomer of Vitamin D2[1].
    5,6-trans-Vitamin D2 (Standard)
  • HY-W747563

    11-trans LTD4

    Drug Isomer Others
    11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.
    11-trans Leukotriene D4
  • HY-W718351

    C18:1(8Z); cis-8-Octadecenoate; Δ8-cis-Octadecenoic acid

    Endogenous Metabolite Metabolic Disease
    cis-8-Octadecenoic acid is a monounsaturated fatty acid and an isomer of oleic acid (HY-N1446), trans-vaccenic acid (HY-113427), trans-petroselinic acid, and cis-petroselinic acid. It has been found in partially hydrogenated vegetable oil and milk fat.
    (Z)-Octadec-8-enoic acid
  • HY-135023

    5-trans Prostaglandin E2

    Cytochrome P450 Prostaglandin Receptor Cancer
    5-trans-PGE2 (5-trans Prostaglandin E2) is the active isomer of PGE2 and a potent activator of aromatase. Supplements the process of paracrine signaling between epithelial cells (expressing high levels of PGE2) and surrounding stromal cells (expressing high levels of aromatase). This process is involved in the growth and development of breast cancer .
    5-trans-PGE2
  • HY-B0191AS

    5,6-trans-AGN 192024-d5

    Isotope-Labeled Compounds Prostaglandin Receptor Cancer
    5,6-trans-Bimatoprost-d5 (5,6-trans-AGN 192024-d5) is the deuterium labeled 5,6-trans-Bimatoprost (HY-B0191A). 5,6-trans-Bimatoprost is the isomer of Bimatoprost (HY-B0191), and can be used as an experimental control. Bimatoprost is a prostaglandin analogue that can be used in studies of ocular hypertension and glaucoma and also has anti-fat formation effects.
    5,6-trans-Bimatoprost-d5
  • HY-135023R

    5-trans Prostaglandin E2 (Standard)

    Cytochrome P450 Prostaglandin Receptor Reference Standards Cancer
    5-trans-PGE2 (Standard) is the analytical standard of 5-trans-PGE2. This product is intended for research and analytical applications. 5-trans-PGE2 (5-trans Prostaglandin E2) is the active isomer of PGE2 and a potent activator of aromatase. Supplements the process of paracrine signaling between epithelial cells (expressing high levels of PGE2) and surrounding stromal cells (expressing high levels of aromatase). This process is involved in the growth and development of breast cancer .
    5-trans-PGE2 (Standard)
  • HY-176106

    Opioid Receptor Others
    1-Naphthyl U-47700 is an α-isomer. 1-Naphthyl U-47700 is a racemic mixtures of the trans-isomers [R,R and S,S]. 1-Naphthyl U-47700 activates MOR in a concentration-dependent manner (EC50 > 23 μM) .
    1-Naphthyl U-47700
  • HY-129764A

    17-trans-PGF3α

    P-glycoprotein Drug Isomer Inflammation/Immunology
    (17E)-Prostaglandin F3α (17-trans-PGF3α) is a double bond isomer of Prostaglandin F3α (HY-129764) and a potential metabolite of trans dietary fatty acids. (17E)-Prostaglandin F3α has anti-inflammatory activity .
    (17E)-Prostaglandin F3α
  • HY-130317

    trans-δ2-11-Methyl-dodecenoic acid

    Fungal Infection
    trans-11-Methyl-2-dodecenic acid is a isomer of cis-11-Methyl-2-dodecenoic acid (HY-134215). cis-11-Methyl-2-dodecenoic acid is a quorum sensing (QS) signal that acts as a diffusion signaling factor (DSF) in extracellular microbial and fungal communication systems .
    trans-11-Methyl-2-dodecenic acid
  • HY-169234

    Cholinesterase (ChE) Neurological Disease
    BChE-IN-35 (Azo-9) is a BChE inhibitor. BChE-IN-35 has a dynamic cis/trans conformational change, where the cis isomer preferentially binds to BChE. BChE-IN-35 can be used in Alzheimer's disease (AD) research .
    BChE-IN-35
  • HY-B0584A

    5,6-trans-Fluprostenol isopropyl ester; 5,6-trans-AL6221; 5,6-trans-Flu-Ipr

    Prostaglandin Receptor Endocrinology
    5,6-trans-Travoprost is the isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
    5,6-trans-Travoprost
  • HY-N8356

    13-cis-Retinyl palmitate

    Endogenous Metabolite Others
    13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate) is a 13-cis isomer formed by vitamin A palmitate in corn flakes. 13-cis-Vitamin A palmitate has a biological activity of 75% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A .
    13-cis-Vitamin A palmitate
  • HY-117583

    HDAC Histone Methyltransferase Neurological Disease
    cis-BG47 is an cis-isomer of BG47, BG47 is a prototypical histone deacetylases HDAC1 and HDAC2 selective, optoepigenetic probe. BG47 can bind to and competitively inhibits the deacetylase activity of HDAC targets upon a light-induced trans-to-cis isomerization, and increases Histone Methyltransferase H3K9 acetylation. cis-BG47 can be used for neurological disease research .
    cis-BG47

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: