SF-1 antagonist-1
SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of ＜200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 2842079-86-9
- Formula: C22H18F4N6O3
- Molecular Weight:490.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SF-1 antagonist-1 (0-20 μM) affects SF-1 transcriptional activity with an EC50 value of ＜200 nM[1]. SF-1 antagonist-1 (0-20 μM; 48 h) affects proliferation of R2C cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Rat Leydig tumor cell line, R2C
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Concentration:0-20 μM
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Incubation Time:48 h
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Result:Inhibited proliferation of R2C cells with an EC50 value of ＜200 nM.
Chemical Information
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CAS No. 2842079-86-9
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Molecular Weight 490.41
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Formula C22H18F4N6O3
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SMILES
FC(F)(F)C(C=C1)=CC=C1NC2=NN(C)C3=C2N=CN(CC(NC4=CC=C(OC)C(F)=C4)=O)C3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SF-1 antagonist-1 Related Classifications
HY-148259 Related Classifications
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