SGB-1534 hydrochloride
SGB-1534 hydrochloride is an orally active, selective and competitive antagonist of the alpha 1-adrenoceptor and the 5-HT2 receptor. SGB-1534 hydrochloride can inhibit vasoconstriction and lower blood pressure. SGB-1534 hydrochloride can be used for the research of cardiovascular disease, such as hypertension.
For research use only. We do not sell to patients.
- CAS No.: 88068-72-8
- Formula: C21H25ClN4O3
- Molecular Weight:416.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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α1-adrenergic receptor |
5-HT2 Receptor |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 88068-72-8
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Molecular Weight 416.90
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Formula C21H25ClN4O3
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SMILES
O=C(N1CCN2CCN(C3=C(C=CC=C3)OC)CC2)C4=CC=CC=C4NC1=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Aono J, et al. Mechanism of the hypotensive effect of a novel phenylpiperazine derivative, SGB-1534: antagonism at alpha 1-adrenergic and 5-HT2 receptors. Arch Int Pharmacodyn Ther. 1985 Sep;277(1):126-39. [Content Brief]
[2]. Nabata H, et al. Antihypertensive effects of a novel phenylpiperazine derivative, SGB-1534, on several hypertensive models of rats. Arch Int Pharmacodyn Ther. 1985 Sep;277(1):104-18. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SGB-1534 hydrochloride Related Classifications
HY-106418A Related Classifications
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