SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
For research use only. We do not sell to patients.
- CAS No.: 64987-85-5
- Formula: C16H18N2O6
- Molecular Weight:334.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-42360
SMCCProtein Crosslinker -
HY-D0975
Sulfo-SMCC sodiumADC Linker -
HY-W041994
GMBSPrimary Amines and Sulfhydryl Groups Cross-Linker -
HY-12362
Val-cit-PAB-OHADC Linker -
HY-100216
SPDPADC linker -
HY-42146
BMPSADC Linker -
HY-78961
6-Maleimidohexanoic acid N-hydroxysuccinimide esterADC Linker -
HY-20336
Mc-Val-Cit-PABC-PNPADC Linker -
HY-W019543
Disuccinimidyl suberate CrosslinkerCrosslinker -
HY-15575
VcMMAEDrug-Linker Conjugate for ADC -
HY-41189
Fmoc-Val-Cit-PAB-PNPADC Linker -
HY-78738
MC-Val-Cit-PABADC Linker
Biological Activity
Description
In Vitro
SMCC or sulfo-SMCC can use to conjugate keyhole limpet hemocyanin (KLH) and ovalbumin (OVA). In the the conjugation system, 300 μl KLH or OVA (3 mg) and 30 μl SMCC or Sulfo-SMCC (the final concentration of 0.1 mM) are added in PBS with final volume of 3 ml[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 64987-85-5
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Molecular Weight 334.32
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Formula C16H18N2O6
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SMILES
O=C(C1CCC(CN2C(C=CC2=O)=O)CC1)ON3C(CCC3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SMCC (GMP) Related Classifications
HY-42360G Related Classifications
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