TDO-IN-2

TDO-IN-2 (Compound 5c) is an orally active TDO inhibitor (IC50: 1.25 μM). TDO-IN-2 has antitumor activity in the Hepa1-6 hepatocellular carcinoma allograft mouse model. TDO-IN-2 has synergistic effects with the PD-1/PD-L1 inhibitor BMS-202 (HY-19745) and can be used to study tumor immune tolerance.

For research use only. We do not sell to patients.

  • Formula: C20H15N3O3
  • Molecular Weight:345.35
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Indoleamine 2,3-Dioxygenase (IDO) Isoforms

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