TDO-IN-2
TDO-IN-2 (Compound 5c) is an orally active TDO inhibitor (IC50: 1.25 μM). TDO-IN-2 has antitumor activity in the Hepa1-6 hepatocellular carcinoma allograft mouse model. TDO-IN-2 has synergistic effects with the PD-1/PD-L1 inhibitor BMS-202 (HY-19745) and can be used to study tumor immune tolerance.
For research use only. We do not sell to patients.
- Formula: C20H15N3O3
- Molecular Weight:345.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 345.35
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Formula C20H15N3O3
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SMILES
O=C(/C(C#N)=C/C1=CNC2=CC=CC=C12)NC3=CC(OCCO4)=C4C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)