2. Neuronal Signaling
  3. Amyloid-β
  4. ACI-19626

ACI-19626  (Synonyms: TDP-43-IN-2)

製品番号: HY-163575 純度: 98.52%
COA 取扱説明書 Technical Support

ACI-19626 (TDP-43-IN-2) is a TDP-43 aggregation inhibitor that can be used in the research of neurodegenerative diseases.

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ACI-19626

ACI-19626 構造式

CAS 番号 : 3033951-93-5

容量 価格（税別） 在庫状況 数量
1 mg $195 在庫あり
5 mg $480 在庫あり
10 mg $690 在庫あり
25 mg $1080 在庫あり
50 mg $1490 在庫あり
100 mg $2200 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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ACI-19626 関連抗体

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製品説明

ACI-19626 (TDP-43-IN-2) is a TDP-43 aggregation inhibitor that can be used in the research of neurodegenerative diseases[1][2].

体外実験

ACI-19626 (compound 17) inhibits TDP-43 aggregates with a Ki value of 22 nM[1].
[18F]ACI-19626 can serve as a PET imaging agent for TDP-43 pathology[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ACI-19626 関連抗体
分子量

439.51

分子式

C22H22FN5O2S
CAS 番号
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(CCN1C3=CC=CN=C3)N=C(C4=C(F)N=C(N5CCC(CC5)CO)C=C4)S2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 5 mg/mL (11.38 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2753 mL 11.3763 mL 22.7526 mL
5 mM 0.4551 mL 2.2753 mL 4.5505 mL
10 mM 0.2275 mL 1.1376 mL 2.2753 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

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体積 （開始）

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純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2753 mL 11.3763 mL 22.7526 mL 56.8815 mL
5 mM 0.4551 mL 2.2753 mL 4.5505 mL 11.3763 mL
10 mM 0.2275 mL 1.1376 mL 2.2753 mL 5.6882 mL
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ACI-19626 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ACI-196263033951-93-5TDP-43-IN-2ACI19626ACI 19626Amyloid-ββ-amyloid peptideAβAbetamyotrophic lateral sclerosisAlzheimer’s diseaseFrontotemporal dementiaInhibitorinhibitorinhibit

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製品名:
ACI-19626
製品番号:
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