Tetrandrine 2'-N-β-oxide
Tetrandrine 2'-N-β-oxide is an anti-hyperglycemic dibenzylisoquinoline alkaloid. At a dose of 1 mg/kg, Tetrandrine 2'-N-β-oxide can reduce hyperglycemia levels in streptozotocin (HY-13753)-induced diabetic mice to nearly 50% of their original levels. Tetrandrine 2'-N-β-oxide is primarily used in research related to the anti-hyperglycemic of type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 62828-25-5
- Formula: C38H42N2O7
- Molecular Weight:638.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 62828-25-5
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Molecular Weight 638.75
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Formula C38H42N2O7
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SMILES
COC1=C2C3=C(CCN([C@@]3([H])CC4=CC=C(OC)C(OC5=CC=C(C[C@@]6([H])C7=CC(O2)=C(C=C7CC[N@+]6([O-])C)OC)C=C5)=C4)C)C=C1OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tsutsumi T, et al. Anti-hyperglycemic effect of fangchinoline isolated from Stephania tetrandra Radix in streptozotocin-diabetic mice. Biol Pharm Bull. 2003 Mar;26(3):313-7. [Content Brief]
[2]. Jung M, et al. Antidiabetic agents from medicinal plants. Curr Med Chem. 2006;13(10):1203-18. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)