Thiomichler's ketone
Based on 1 Customer Validation
Thiomichler's ketone (4,4'-Bis (dimethylamino) thiobenzophenone) is a heavy metal complexing agent and a colorimetric/spectrophotometric reagent. Thiomichler's ketone shows selectivity for Hg2+ at pH 3, and exhibits activity towards Pd2+ and Ag+ at pH 3.5. Thiomichler's ketone enables accurate detection of trace Pd2+ by forming an extractable Hg2+ complex via micelle-mediated cloud point extraction, or generating a red coordination complex including Pd (TMK)4. Thiomichler's ketone is applicable for the determination of trace Pd2+ in antibiotics and catalysts of automobile exhaust purifiers.
For research use only. We do not sell to patients.
- Purity: 81.08%
- CAS No.: 1226-46-6
- Formula: C17H20N2S
- Molecular Weight:284.42
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Thiomichler's ketone (2.2×10-5 mol L-1; 15 min at 50 °C) acts as a selective and sensitive chromogenic reagent for spectrophotometric determination of Hg2+ in aqueous solutions and water samples via cloud point extraction, enabling detection of Hg2+ down to 0.83 ng mL-1 with excellent reproducibility and recovery[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1226-46-6
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Appearance Solid
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Molecular Weight 284.42
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Formula C17H20N2S
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Color Brown to reddish brown
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SMILES
CN(C1=CC=C(C(C2=CC=C(N(C)C)C=C2)=S)C=C1)C
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Synonyms
4,4'-Bis(dimethylamino)thiobenzophenone
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Ethanol : 0.25 mg/mL (0.88 mM; ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Niazi A, et al. Spectrophotometric determination of mercury in water samples after cloud point extraction using nonionic surfactant Triton X-114. J Hazard Mater. 2009;165(1-3):1200-1203. [Content Brief]
[2]. Niazi A, et al. Simultaneous spectrophotometric determination of mercury and palladium with Thio-Michler's Ketone using partial least squares regression and orthogonal signal correction. Spectrochim Acta A Mol Biomol Spectrosc. 2008;71(3):1172-1177. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thiomichler's ketone Related Classifications
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