Tofacitinib impurity 2

Cat. No.: HY-40349A Purity: 95.42%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Tofacitinib impurity 2 is an impurity of Tofacitinib (HY-40354).

For research use only. We do not sell to patients.

Tofacitinib impurity 2 Chemical Structure

Size	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Liquid
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote
10 g	Get quote

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Description

Tofacitinib impurity 2 is an impurity of Tofacitinib (HY-40354).

Molecular Weight

436.69

Formula

C₂₈H₄₄N₄

Appearance

Liquid

SMILES

C[C@@H]1CCN(CC2=CC=CC=C2)C[C@@H]1NC.C[C@H]3CCN(CC4=CC=CC=C4)C[C@H]3NC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (229.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2900 mL	11.4498 mL	22.8995 mL
5 mM	0.4580 mL	2.2900 mL	4.5799 mL
10 mM	0.2290 mL	1.1450 mL	2.2900 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.42%

Select Batch:

Data Sheet (247 KB) SDS (251 KB)

COA (255 KB) LCMS (101 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2900 mL	11.4498 mL	22.8995 mL	57.2488 mL
	5 mM	0.4580 mL	2.2900 mL	4.5799 mL	11.4498 mL
	10 mM	0.2290 mL	1.1450 mL	2.2900 mL	5.7249 mL
	15 mM	0.1527 mL	0.7633 mL	1.5266 mL	3.8166 mL
	20 mM	0.1145 mL	0.5725 mL	1.1450 mL	2.8624 mL
	25 mM	0.0916 mL	0.4580 mL	0.9160 mL	2.2900 mL
	30 mM	0.0763 mL	0.3817 mL	0.7633 mL	1.9083 mL
	40 mM	0.0572 mL	0.2862 mL	0.5725 mL	1.4312 mL
	50 mM	0.0458 mL	0.2290 mL	0.4580 mL	1.1450 mL
	60 mM	0.0382 mL	0.1908 mL	0.3817 mL	0.9541 mL
	80 mM	0.0286 mL	0.1431 mL	0.2862 mL	0.7156 mL
	100 mM	0.0229 mL	0.1145 mL	0.2290 mL	0.5725 mL