TriOncoFAP-GlyPro-MMAE
TriOncoFAP-GlyPro-MMAE is a small molecule drug conjugate (SMDC) targeting fibroblast activation protein (FAP) with an IC50 of 13 pmol/L. TriOncoFAP-GlyPro-MMAE combines a FAP-targeting ligand (TriOnco), a cleavable glycine-proline linker, and a cytotoxic payload (MMAE).
For research use only. We do not sell to patients.
- Formula: C167H218F6N36O43S
- Molecular Weight:3563.79
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 3563.79
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Formula C167H218F6N36O43S
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SMILES
O=C(NCCNC(CCOCC(COCCC(NCCNC(CCC(NC1=CC=CC2=C1N=CC=C2C(NCC(N3CC(C[C@H]3C#N)(F)F)=O)=O)=O)=O)=O)(COCCC(NCCNC(CCC(NC4=C(N=CC=C5C(NCC(N6CC(C[C@H]6C#N)(F)F)=O)=O)C5=CC=C4)=O)=O)=O)NC(CCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CSC7C(N(C(C7)=O)CCCCCC(NCC(N8[C@@H](CCC8)C(NC9=CC=C(C=C9)COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(N%10[C@]([H])([C@@H]([C@H](C(N[C@@H]([C@@H](O)C%11=CC=CC=C%11)C)=O)C)OC)CCC%10)=O)OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)=O)=O)=O)=O)C(O)=O)=O)CC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)=O)=O)CCC(NC%12=CC=CC%13=C%12N=CC=C%13C(NCC(N%14[C@H](C#N)CC(C%14)(F)F)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)