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Cat. No.: HY-N1357A

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Rauvotetraphylline E perchlorate

Rauvotetraphylline E perchlorate is an indole alkaloid. Rauvotetraphylline E perchlorate can be isolated from the aerial parts of Rauvolfia tetraphylla. Rauvotetraphylline E perchlorate is inactive against multiple cancers. Rauvotetraphylline E perchlorate can be used in cancer research.

For research use only. We do not sell to patients.

CAS No.: 2896194-26-4
Formula: C₂₀H₁₉ClN₂O₇
Molecular Weight:434.83

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Rauvotetraphylline E perchlorate Chemical Structure

CAS No.: 2896194-26-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC50	40 μM	Cytotoxicity against human HL-60 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM. Cytotoxicity against human HL-60 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM.	s13659-012-0012-5
SMMC-7721	IC50	40 μM	Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM. Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM.	s13659-012-0012-5
A549	IC50	40 μM	Cytotoxicity against human A-549 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM. Cytotoxicity against human A-549 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM.	s13659-012-0012-5
MCF7	IC50	40 μM	Cytotoxicity against human MCF-7 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM. Cytotoxicity against human MCF-7 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM.	s13659-012-0012-5
SW480	IC50	40 μM	Cytotoxicity against human SW-480 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM. Cytotoxicity against human SW-480 cells assessed as reduction in cell viability by MTT assay with IC50 > 40 μM.	s13659-012-0012-5

In Vitro

Rauvotetraphylline E perchlorate is inactive against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cancer cell lines, exhibiting an IC₅₀ value greater than 40 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 2896194-26-4
Molecular Weight 434.83
Formula C₂₀H₁₉ClN₂O₇
SMILES

O=Cl(=O)([O-])=O.OC(C1=CO[C@@H](C)[C@]2([H])C[N+]3=C(C4=C(C=C3)C5=CC=CC=C5N4)C[C@]12[H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gao, Y., et al. Rauvotetraphyllines A-E, new indole alkaloids from Rauvolfia tetraphylla. Nat. Prod. Bioprospect. 2, 65–69 (2012).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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