country

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N12603

Copy Link Print Information

Typhatifolin B

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion.

For research use only. We do not sell to patients.

Formula: C₃₄H₃₂O₅
Molecular Weight:520.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Typhatifolin B Chemical Structure

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
4T1	IC₅₀	2.82 μM Compound: 2; TTB	Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay	[PMID: 38387332]
A549	IC₅₀	3.21 μM Compound: 2; TTB	Cytotoxicity against human A549 cells assessed as cell viability by MTT assay Cytotoxicity against human A549 cells assessed as cell viability by MTT assay	[PMID: 38387332]
BEAS-2B	IC₅₀	5.27 μM Compound: 2; TTB	Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay	[PMID: 38387332]
HeLa	IC₅₀	2.2 μM Compound: 2; TTB	Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay	[PMID: 38387332]
HFF	IC₅₀	5.91 μM Compound: 2; TTB	Cytotoxicity against human HFF cells assessed as cell viability by MTT assay Cytotoxicity against human HFF cells assessed as cell viability by MTT assay	[PMID: 38387332]
MCF7	IC₅₀	8.64 μM Compound: 2; TTB	Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay	[PMID: 38387332]
MDA-MB-231	IC₅₀	4.33 μM Compound: 2; TTB	Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay	[PMID: 38387332]

In Vitro

Typhatifolin B (Compd 2) exhibits IC₅₀ values of 4.33 μM, 8.64 μM, 2.82 μM, 2.20 μM, 3.21 μM, 5.27 μM in MDA-MB231, MCF-7, 4T1, Hela, A549, BEAS-2B, HFF cells, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 520.61
Formula C₃₄H₃₂O₅
SMILES

O=C1C[C@@](OC2=C1C(O)=C([C@@](/C=C/C[C@@H](O)CCC3=CC=CC=C3)([H])C4=CC=CC=C4)C(O)=C2)([H])C5=CC=CC=C5
Structure Classification
- Flavonoids
- Flavonones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yu-Peng Li, et al. Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway. European Journal of Medicinal Chemistry. Volume 268, 15 March 2024, 116220.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Get Quote In-stock