Tyrphostin AG 1288
Based on 1 Customer Validation
Tyrphostin AG 1288 is a potent Tyrosine Kinase inhibitor. Tyrphostin AG 1288 inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
For research use only. We do not sell to patients.
- Purity: 98.68%
- CAS No.: 116313-73-6
- Formula: C10H5N3O4
- Molecular Weight:231.16
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 116313-73-6
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Appearance Solid
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Molecular Weight 231.16
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Formula C10H5N3O4
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Color Light yellow to yellow
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SMILES
N#C/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
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Synonyms
AG 1288
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 125 mg/mL (540.75 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3260 mL | 21.6300 mL | 43.2601 mL | 108.1502 mL |
| 5 mM | 0.8652 mL | 4.3260 mL | 8.6520 mL | 21.6300 mL | |
| 10 mM | 0.4326 mL | 2.1630 mL | 4.3260 mL | 10.8150 mL | |
| 15 mM | 0.2884 mL | 1.4420 mL | 2.8840 mL | 7.2100 mL | |
| 20 mM | 0.2163 mL | 1.0815 mL | 2.1630 mL | 5.4075 mL | |
| 25 mM | 0.1730 mL | 0.8652 mL | 1.7304 mL | 4.3260 mL | |
| 30 mM | 0.1442 mL | 0.7210 mL | 1.4420 mL | 3.6050 mL | |
| 40 mM | 0.1082 mL | 0.5408 mL | 1.0815 mL | 2.7038 mL | |
| 50 mM | 0.0865 mL | 0.4326 mL | 0.8652 mL | 2.1630 mL | |
| 60 mM | 0.0721 mL | 0.3605 mL | 0.7210 mL | 1.8025 mL | |
| 80 mM | 0.0541 mL | 0.2704 mL | 0.5408 mL | 1.3519 mL | |
| 100 mM | 0.0433 mL | 0.2163 mL | 0.4326 mL | 1.0815 mL |