VA-K-14 hydrochloride
Based on 1 Customer Validation
VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM).
For research use only. We do not sell to patients.
- Purity: 98.96%
- CAS No.: 1171341-19-7
- Formula: C18H16ClN3S
- Molecular Weight:341.86
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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CAS No. 1171341-19-7
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Appearance Solid
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Molecular Weight 341.86
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Formula C18H16ClN3S
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Color Off-white to gray
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SMILES
CNC1=NC(C2=C(C3=CC=CC=C3)NC4=C2C=CC=C4)=CS1.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 50 mg/mL (146.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9252 mL | 14.6259 mL | 29.2517 mL | 73.1294 mL |
| 5 mM | 0.5850 mL | 2.9252 mL | 5.8503 mL | 14.6259 mL | |
| 10 mM | 0.2925 mL | 1.4626 mL | 2.9252 mL | 7.3129 mL | |
| 15 mM | 0.1950 mL | 0.9751 mL | 1.9501 mL | 4.8753 mL | |
| 20 mM | 0.1463 mL | 0.7313 mL | 1.4626 mL | 3.6565 mL | |
| 25 mM | 0.1170 mL | 0.5850 mL | 1.1701 mL | 2.9252 mL | |
| 30 mM | 0.0975 mL | 0.4875 mL | 0.9751 mL | 2.4376 mL | |
| 40 mM | 0.0731 mL | 0.3656 mL | 0.7313 mL | 1.8282 mL | |
| 50 mM | 0.0585 mL | 0.2925 mL | 0.5850 mL | 1.4626 mL | |
| 60 mM | 0.0488 mL | 0.2438 mL | 0.4875 mL | 1.2188 mL | |
| 80 mM | 0.0366 mL | 0.1828 mL | 0.3656 mL | 0.9141 mL | |
| 100 mM | 0.0293 mL | 0.1463 mL | 0.2925 mL | 0.7313 mL |