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Cat. No.: HY-N21847

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Versicolorone

Versicolorone is an anthraquinone-type aflatoxin biosynthetic intermediate that serves as a substrate for VHA reductase in the aflatoxin metabolic network and is enzymatically converted to sterigmatocystin acetate, elucidating the aflatoxin biotransformation pathway. Versicolorone can be used in studies on the toxicity and carcinogenic mechanisms associated with aflatoxin contamination.

For research use only. We do not sell to patients.

CAS No.: 84062-31-7
Formula: C₂₀H₁₆O₇
Molecular Weight:368.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Versicolorone Chemical Structure

CAS No.: 84062-31-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Versicolorone (25 days) is a novel anthraquinone metabolite isolated from the Aspergillus versicolor strain ATCC 34508^[2].
Versicolorone, upon incubation (up to 60 min) with cytosolic fractions of Aspergillus parasiticus NIAH‑26 in the presence of NADPH, is biotransformed into sterigmatocystin acetate, sterigmatocystin, and minor amounts of versicolorol^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 84062-31-7
Molecular Weight 368.34
Formula C₂₀H₁₆O₇
SMILES

O=C1C2=C(C(C3=C(C4=C(C=C13)OCC4CCC(C)=O)O)=O)C(O)=CC(O)=C2
Structure Classification
- Quinones
- Anthraquinones
Initial Source
- Microorganisms
Aspergillus versicolor
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wen Y, et al. Function of the cypX and moxY genes in aflatoxin biosynthesis in Aspergillus parasiticus. Applied and environmental microbiology. 2005 Jun;71(6):3192-8.

[2]. M. Berger-Deguee, et al. Structure of versicolorone isolated from Aspergillus versicolor, Phytochemistry, Volume 21, Issue 6, 1982, Pages 1449-1451, ISSN 0031-9422.

[3]. Yabe K, et al. Enzymatic conversion of averufin to hydroxyversicolorone and elucidation of a novel metabolic grid involved in aflatoxin biosynthesis. Applied and environmental microbiology. 2003 Jan;69(1):66-73.

[4]. Craig A, et al. Hydroxyversicolorone: isolation and characterization of a potential intermediate in aflatoxin biosynthesis. Journal of Organic Chemistry 1 May 1988; 53 (11): 2472-2477.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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