84062-31-7
84062-31-7
Chemical Structure
Versicolorone
- CAS No.: 84062-31-7
- Formula:C20H16O7
- Molecular Weight:368.34
InChIKey: XDLBESHDJXFECS-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C3=C(C4=C(C=C13)OCC4CCC(C)=O)O)=O)C(O)=CC(O)=C2
Biological Activity: Versicolorone is an anthraquinone-type aflatoxin biosynthetic intermediate that serves as a substrate for VHA reductase in the aflatoxin metabolic network and is enzymatically converted to sterigmatocystin acetate, elucidating the aflatoxin biotransformation pathway. Versicolorone can be used in studies on the toxicity and carcinogenic mechanisms associated with aflatoxin contamination[1][2][3][4].
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Versicolorone | Versicolorone is an anthraquinone-type aflatoxin biosynthetic intermediate that serves as a substrate for VHA reductase in the aflatoxin metabolic network and is enzymatically converted to sterigmatocystin acetate, elucidating the aflatoxin biotransformation pathway. Versicolorone can be used in studies on the toxicity and carcinogenic mechanisms associated with aflatoxin contamination. | |||||||||||||||||||||
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References
- [1]. Wen Y, et al. Function of the cypX and moxY genes in aflatoxin biosynthesis in Aspergillus parasiticus. Applied and environmental microbiology. 2005 Jun;71(6):3192-8.
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[2]. M. Berger-Deguee, et al. Structure of versicolorone isolated from Aspergillus versicolor, Phytochemistry, Volume 21, Issue 6, 1982, Pages 1449-1451, ISSN 0031-9422.
- [3]. Yabe K, et al. Enzymatic conversion of averufin to hydroxyversicolorone and elucidation of a novel metabolic grid involved in aflatoxin biosynthesis. Applied and environmental microbiology. 2003 Jan;69(1):66-73.
- [4]. Craig A, et al. Hydroxyversicolorone: isolation and characterization of a potential intermediate in aflatoxin biosynthesis. Journal of Organic Chemistry 1 May 1988; 53 (11): 2472-2477.
