2. Metabolic Enzyme/Protease
  3. Phospholipase
  4. VU0364739

VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation.

For research use only. We do not sell to patients.

VU0364739 Chemical Structure

VU0364739 Chemical Structure

CAS No. : 1244639-78-8

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5 mg USD 480 In-stock
10 mg USD 800 In-stock
25 mg USD 1550 In-stock
50 mg USD 2400 In-stock
100 mg USD 3600 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation[1].

IC50 & Target

PLD[1]
Molecular Weight

446.52

Formula

C26H27FN4O2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=CC2=C(C=CC=C2)C=C1)NCCN3CCC4(CC3)C(NCN4C5=CC(F)=CC=C5)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (447.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2395 mL 11.1977 mL 22.3954 mL
5 mM 0.4479 mL 2.2395 mL 4.4791 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2395 mL 11.1977 mL 22.3954 mL 55.9885 mL
5 mM 0.4479 mL 2.2395 mL 4.4791 mL 11.1977 mL
10 mM 0.2240 mL 1.1198 mL 2.2395 mL 5.5989 mL
15 mM 0.1493 mL 0.7465 mL 1.4930 mL 3.7326 mL
20 mM 0.1120 mL 0.5599 mL 1.1198 mL 2.7994 mL
25 mM 0.0896 mL 0.4479 mL 0.8958 mL 2.2395 mL
30 mM 0.0747 mL 0.3733 mL 0.7465 mL 1.8663 mL
40 mM 0.0560 mL 0.2799 mL 0.5599 mL 1.3997 mL
50 mM 0.0448 mL 0.2240 mL 0.4479 mL 1.1198 mL
60 mM 0.0373 mL 0.1866 mL 0.3733 mL 0.9331 mL
80 mM 0.0280 mL 0.1400 mL 0.2799 mL 0.6999 mL
100 mM 0.0224 mL 0.1120 mL 0.2240 mL 0.5599 mL
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VU0364739 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VU03647391244639-78-8VU 0364739VU-0364739PhospholipaseMDA-MB-231cancerproliferationInhibitorinhibitorinhibit

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