VU6036720 hydrochloride
Based on 1 Customer Validation
VU6036720 hydrochloride is a potent and specific in vitro inhibitor of Kir4.1/5.1. VU6036720 hydrochloride can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM. VU6036720 hydrochloride can be used for the research of brain and kidney.
For research use only. We do not sell to patients.
- Purity: 99.65%
- Formula: C20H23Cl2FN4O2S
- Molecular Weight:473.39
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 473.39
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Formula C20H23Cl2FN4O2S
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Color Off-white to gray
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SMILES
C[C@H]1CN(CCN1CCNS(=O)(C2=CC(Cl)=C(C=C2)F)=O)C3=C(C#N)C=CC=C3.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 40 mg/mL (84.50 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1124 mL | 10.5621 mL | 21.1242 mL | 52.8106 mL |
| 5 mM | 0.4225 mL | 2.1124 mL | 4.2248 mL | 10.5621 mL | |
| 10 mM | 0.2112 mL | 1.0562 mL | 2.1124 mL | 5.2811 mL | |
| 15 mM | 0.1408 mL | 0.7041 mL | 1.4083 mL | 3.5207 mL | |
| 20 mM | 0.1056 mL | 0.5281 mL | 1.0562 mL | 2.6405 mL | |
| 25 mM | 0.0845 mL | 0.4225 mL | 0.8450 mL | 2.1124 mL | |
| 30 mM | 0.0704 mL | 0.3521 mL | 0.7041 mL | 1.7604 mL | |
| 40 mM | 0.0528 mL | 0.2641 mL | 0.5281 mL | 1.3203 mL | |
| 50 mM | 0.0422 mL | 0.2112 mL | 0.4225 mL | 1.0562 mL | |
| 60 mM | 0.0352 mL | 0.1760 mL | 0.3521 mL | 0.8802 mL | |
| 80 mM | 0.0264 mL | 0.1320 mL | 0.2641 mL | 0.6601 mL |