VY7523
VY7523 is a monoclonal antibody and a selective inhibitor of pathological Tau. VY7523 reduces the propagation of pathogenic Tau in transgenic mouse models. VY7523 can be used in the research of Alzheimer's disease. The isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG4 kappa
Human
VY7523 exhibits over 200-fold higher selectivity for pathological tau than for recombinant wild-type h-tau[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Tau
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- VY7523
- VY 7523
- VY-7523
- Tau Protein
- healthy volunteers
- human wild-type tau
- pathogenic tau propagation
- early Alzheimer’s disease patients
- C-terminal domain of pathologic tau
- pathologic tau (C-terminal domain)
- transgenic mouse models
- recombinant human wild-type tau
- Alzheimer's disease
- P301S transgenic mice
- Inhibitor
- inhibitor
- inhibit