WAY-297848
Based on 1 Customer Validation
WAY-297848 is an active molecule for the study of amyloid diseases and synucleinopathies.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 404360-27-6
- Formula: C13H13ClN2O2S
- Molecular Weight:296.77
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 404360-27-6
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Appearance Solid
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Molecular Weight 296.77
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Formula C13H13ClN2O2S
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Color White to off-white
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SMILES
CC(C(NC1=NC=CS1)=O)(C)OC2=CC=C(Cl)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : ≥ 30 mg/mL (101.09 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
Purity & Documentation
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Data Sheet (243 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3696 mL | 16.8481 mL | 33.6961 mL | 84.2403 mL |
| 5 mM | 0.6739 mL | 3.3696 mL | 6.7392 mL | 16.8481 mL | |
| 10 mM | 0.3370 mL | 1.6848 mL | 3.3696 mL | 8.4240 mL | |
| 15 mM | 0.2246 mL | 1.1232 mL | 2.2464 mL | 5.6160 mL | |
| 20 mM | 0.1685 mL | 0.8424 mL | 1.6848 mL | 4.2120 mL | |
| 25 mM | 0.1348 mL | 0.6739 mL | 1.3478 mL | 3.3696 mL | |
| 30 mM | 0.1123 mL | 0.5616 mL | 1.1232 mL | 2.8080 mL | |
| 40 mM | 0.0842 mL | 0.4212 mL | 0.8424 mL | 2.1060 mL | |
| 50 mM | 0.0674 mL | 0.3370 mL | 0.6739 mL | 1.6848 mL | |
| 60 mM | 0.0562 mL | 0.2808 mL | 0.5616 mL | 1.4040 mL | |
| 80 mM | 0.0421 mL | 0.2106 mL | 0.4212 mL | 1.0530 mL | |
| 100 mM | 0.0337 mL | 0.1685 mL | 0.3370 mL | 0.8424 mL |
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