WAY-622252
Based on 1 Customer Validation
WAY-622252 is an active molecule for the study of amyloid diseases and synucleinopathies.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 1897-80-9
- Formula: C15H11FN2O
- Molecular Weight:254.26
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 1897-80-9
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Appearance Solid
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Molecular Weight 254.26
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Formula C15H11FN2O
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Color White to off-white
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SMILES
O=C1N(C2=CC=C(F)C=C2)C(C)=NC3=C1C=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (393.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
Purity & Documentation
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Data Sheet (243 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9330 mL | 19.6649 mL | 39.3298 mL | 98.3246 mL |
| 5 mM | 0.7866 mL | 3.9330 mL | 7.8660 mL | 19.6649 mL | |
| 10 mM | 0.3933 mL | 1.9665 mL | 3.9330 mL | 9.8325 mL | |
| 15 mM | 0.2622 mL | 1.3110 mL | 2.6220 mL | 6.5550 mL | |
| 20 mM | 0.1966 mL | 0.9832 mL | 1.9665 mL | 4.9162 mL | |
| 25 mM | 0.1573 mL | 0.7866 mL | 1.5732 mL | 3.9330 mL | |
| 30 mM | 0.1311 mL | 0.6555 mL | 1.3110 mL | 3.2775 mL | |
| 40 mM | 0.0983 mL | 0.4916 mL | 0.9832 mL | 2.4581 mL | |
| 50 mM | 0.0787 mL | 0.3933 mL | 0.7866 mL | 1.9665 mL | |
| 60 mM | 0.0655 mL | 0.3277 mL | 0.6555 mL | 1.6387 mL | |
| 80 mM | 0.0492 mL | 0.2458 mL | 0.4916 mL | 1.2291 mL | |
| 100 mM | 0.0393 mL | 0.1966 mL | 0.3933 mL | 0.9832 mL |
WAY-622252 Related Classifications
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