WAY-658674
Based on 1 Customer Validation
WAY-658674 is an active molecule for the study of amyloid diseases and synucleinopathies.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 42310-54-3
- Formula: C12H13ClN2O2S
- Molecular Weight:284.77
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 42310-54-3
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Appearance Solid
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Molecular Weight 284.77
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Formula C12H13ClN2O2S
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Color White to off-white
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SMILES
CC1=C(C=CC(Cl)=C1)OCC(NC2=NCCS2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (175.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5116 mL | 17.5582 mL | 35.1163 mL | 87.7908 mL |
| 5 mM | 0.7023 mL | 3.5116 mL | 7.0233 mL | 17.5582 mL | |
| 10 mM | 0.3512 mL | 1.7558 mL | 3.5116 mL | 8.7791 mL | |
| 15 mM | 0.2341 mL | 1.1705 mL | 2.3411 mL | 5.8527 mL | |
| 20 mM | 0.1756 mL | 0.8779 mL | 1.7558 mL | 4.3895 mL | |
| 25 mM | 0.1405 mL | 0.7023 mL | 1.4047 mL | 3.5116 mL | |
| 30 mM | 0.1171 mL | 0.5853 mL | 1.1705 mL | 2.9264 mL | |
| 40 mM | 0.0878 mL | 0.4390 mL | 0.8779 mL | 2.1948 mL | |
| 50 mM | 0.0702 mL | 0.3512 mL | 0.7023 mL | 1.7558 mL | |
| 60 mM | 0.0585 mL | 0.2926 mL | 0.5853 mL | 1.4632 mL | |
| 80 mM | 0.0439 mL | 0.2195 mL | 0.4390 mL | 1.0974 mL | |
| 100 mM | 0.0351 mL | 0.1756 mL | 0.3512 mL | 0.8779 mL |
WAY-658674 Related Classifications
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